K. P. C. Kuypers

2 papers in the library · 288 citations · publishing 2006-2019

Papers

A single inhalation of vapor from dried toad secretion containing 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) in a naturalistic setting is related to sustained enhancement of satisfaction with life, mindfulness-related capacities, and a decrement of psychopathological symptoms.

Psychopharmacology (Berl) April 13, 2019 M. V. Uthaug, R. Lancelotta, K. Van Oorsouw et al. 198 citations

A single inhalation of vapor from dried toad secretion containing 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) in a naturalistic setting is associated with sustained improvements in life satisfaction and mindfulness-related capacities, along with a reduction in psychopathological symptoms.

DOI: 10.1007/s00213-019-05236-w Full text Mental health Psychological health Emotional well-being Mental wellness +25

Stimulant effects of 3,4‐methylenedioxymethamphetamine (MDMA) 75 mg and methylphenidate 20 mg on actual driving during intoxication and withdrawal

Addiction August 8, 2006 J. G. Ramaekers, K. P. C. Kuypers, N. Samyn 90 citations

MDMA, a popular recreational drug in Europe, has stimulant-like effects on driving that vary by task. In a double-blind, placebo-controlled crossover study, 18 recreational MDMA users took 75 mg MDMA, 20 mg methylphenidate, or placebo. During the intoxication phase (3–5 hours after dosing), both MDMA and methylphenidate improved road-tracking performance, reducing the standard deviation of lateral position by about 2 cm compared to placebo. However, MDMA impaired car-following performance, causing subjects to overcorrect in response to speed changes of a leading vehicle. No driving impairments were observed during the withdrawal phase (27–29 hours after dosing).

DOI: 10.1111/j.1360-0443.2006.01566.x MDMA Ecstasy Stimulant Methylphenidate +8