REDUCED PSYCHEDELIC EFFECTS OF KETAMINE INFUSION AFTER ELECTROCONVULSIVE THERAPY: A REPORT ON THREE CASES.
Emmanuel Kiiza Mwesiga, Alinaitwe Racheal, Janet Nakigudde, Seggane Musisi
preprint DOI: 10.31234/osf.io/9w5ub
Summary
AI-generated from the abstractKetamine's psychedelic side effects, which can limit its use for treating suicidal thoughts, may be less intense in patients who have previously undergone electroconvulsive therapy (ECT). In a small comparison, two patients who had received prior ECT reported lower average scores across all domains of a hallucinogen rating scale than one patient who had not. The authors call for more rigorous research to confirm and understand this possible association.
Study at a glance
| Characteristics | Case study Case report |
|---|---|
| Sample size | 3 |
| Population | Patients receiving ketamine infusion for suicide ideations, two with prior ECT and one without |
| Intervention | ketamine infusion |
| Key finding | Patients who received prior ECT had lower mean hallucinogen rating scale scores after ketamine infusion than the patient who did not. |
Abstract
Psychedelic side effects of ketamine limit its use for the treatment of suicide ideations. Psychedelic effects after ketamine infusion were assessed in two patients received prior electroconvulsive therapy (ECT) and one who had not. Patients who received ECT prior to the infusion had lower mean scores on all domains of the hallucinogen rating scale compared to the patient who did not receive prior ECT. Confirming and understanding this association is needed through more rigorous research methods.