The Effects of some Hallucinogens on Aggressiveness of Mice and Rats
W Rewerski, Wojciech Kostowski, T Piechocki, M. Rylski
Pharmacology January 1, 1971 DOI: 10.1159/000136205 via OpenAlex
Summary
AI-generated from the abstractLSD, mescaline, and Sernyl each alter aggression and killing behavior differently depending on the species and dose. LSD reduced aggressiveness in isolated mice. Mescaline strongly reduced aggression in mice but had no effect in rats. Sernyl slightly decreased the killing reaction in rats and either decreased or increased aggression in mice depending on the dose level.
Study at a glance
| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Isolated mice and rats |
| Interventions | LSD mescaline Sernyl |
| Topics | Mescaline |
| Keywords | Hallucinogen Pharmacology Chemistry Psychotomimetic |
| Citations | 19 |
| Key finding | Mescaline strongly reduced aggressiveness in mice but not in rats, while LSD decreased aggressiveness in mice and Sernyl had dose-dependent effects on mouse aggression. |
Abstract
The action of LSD, mescaline and Sernyl® onthe aggressiveness of isolated mice and killing reaction ofrats was investigated. At some dose range, LSD decreased the aggressiveness on isolation time. Mescaline was a strong in mice but not in rats whileSernyl slightly decreased the killing reaction and decreasedor increased the aggressiveness of mice according to dose level.