II. The Effects of Some Hallucinogens on Aggressiveness of Mice and Rats
Wojciech Kostowski, W Rewerski, T Piechocki
Pharmacology January 1, 1972 DOI: 10.1159/000136297 via OpenAlex
Summary
AI-generated from the abstractThe drugs JB-336, psilocybin, ibogaine, and bufotenine all substantially reduced aggressiveness in isolated mice and suppressed muricide (mouse-killing) behavior in rats. The magnitude of this anti-aggressive effect depended on how long the animals had been isolated, the time elapsed since drug injection, and the specific behavioral test employed.
Study at a glance
| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Isolated mice and rats |
| Interventions | JB-336 psilocybin ibogaine bufotenine |
| Topics | Psilocybin |
| Keywords | Hallucinogen Pharmacology Psychotomimetic Neuroscience |
| Citations | 28 |
| Key finding | JB-336, psilocybin, ibogaine, and bufotenine each decreased aggressiveness and muricide behavior, with the effect varying by isolation duration, post-injection time, and test type. |
Abstract
The action of JB-336, psilocybin, ibogaine and bufotenine on the aggressiveness os isolated mice, as well as the muricide reaction of rats, was investigated. All drugs evoked a substantial decrease in aggressiveness, but this effect was dependent on isolation time, time after injection and the type of test used.