The Use of LSD-25 as a Diagnostic Aid in Doubtful Cases of Schizophrenia
The British Journal of Psychiatry January 1, 1965 DOI: 10.1192/bjp.111.470.96 via OpenAlex
Summary
AI-generated from the abstractLSD-25 may exaggerate catatonic and hebephrenic features in people with schizophrenia and produce a caricature of the personality in normal subjects. The drug's primary psychological effect is an exacerbation of existing symptomatology, achieved by weakening central functions and defense systems. Some early investigators considered LSD-25 of limited value as a diagnostic aid in psychiatry.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Intervention | LSD-25 |
| Topics | LSD |
| Keywords | Schizophrenia object-oriented programming Exacerbation Psychiatry Childhood schizophrenia |
| Citations | 14 |
| Key finding | LSD-25 exacerbates existing psychiatric symptoms by weakening central functions and defense systems, and tends to exaggerate catatonic and hebephrenic features in schizophrenics while producing a caricature of personality in normal subjects. |
Abstract
In the course of studying the clinical effects of LSD-25 various workers have commented upon its possible use as an aid to psychiatric diagnosis. Stoll (1947) and Becker (1949) considered it to be of limited value in this respect. Condrau (1949) pointed out that it tended to exaggerate catatonic and hebephrenic features in schizophrenics and to produce a caricature of the personality in normal subjects; the latter point also being made by Anderson and Rawnsley (1954). Von Felsinger et al . (1956) considered the primary psychological effect of the drug to be an exacerbation of existing symptomatology, through a weakening of central functions and defence systems.