Effects of LSD-25 on Relatives of Schizophrenic Patients
G Anastasopoulos, Harry Photiades
Journal of Mental Science January 1, 1962 DOI: 10.1192/bjp.108.452.95 via OpenAlex
Summary
AI-generated from the abstractPatients with schizophrenia who are given LSD-25 experience a worsening of their symptoms and a return to an earlier, more primitive stage of their psychosis, with these manifestations appearing more directly tied to the patients' personal life histories. Additionally, some healthy individuals given the same drug develop paranoid symptoms, though whether hereditary factors influence this reaction remains unknown.
Study at a glance
| Characteristics | Observational study Peer reviewed |
|---|---|
| Population | Schizophrenic patients and normal experimental subjects |
| Intervention | LSD-25 |
| Keywords | Psychopathology Heredity Psychosis Clinical psychology Schizophrenia object-oriented programming |
| Citations | 41 |
| Key finding | LSD-25 increases psychopathological phenomena in schizophrenic patients and can induce paranoid symptoms in some normal subjects, but the role of heredity in the latter is unknown. |
Abstract
Schizophrenic patients given LSD-25 show an increase of psychopathological phenomena and a regression to the prime stage of their psychosis, the manifestations of which seem to be more directly related to the life history of the patients. ∗ It has also been observed that some “normal” experimental subjects show various paranoid symptoms with the same drug, but whether these are in any way determined by heredity is not known.