Study of the Extraction of LSD from Illicit Blotters for HPLC Determination
Journal of Forensic Sciences September 1, 1993 DOI: 10.1520/jfs13514j via OpenAlex
Summary
AI-generated from the abstractThe efficiency of extracting LSD from impregnated papers depends on the extraction method, temperature, time, and solvent. Using the Plackett-Burman design, the optimal conditions for maximal LSD recovery were determined. Quantitative analysis was performed with reversed-phase ion-pair chromatography and UV detection. The extraction procedure's constant and proportional bias were also characterized.
Study at a glance
| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Impregnated papers containing LSD |
| Keywords | Extraction chemistry Solvent Solid phase extraction High-performance liquid chromatography Materials science |
| Citations | 23 |
| Key finding | The optimal extraction conditions for maximal LSD recovery from impregnated papers were determined using a Plackett-Burman experimental design. |
Abstract
Abstract The effect of different parameters (extraction method, temperature, time, solvent) on the extraction efficiency of LSD from impregnated papers has been investigated. Designed experiments have been applied according to the Plackett-Burman method. For the quantitative determination of LSD reversed phase ion-pair chromatography has been used with UV detection. The experimental conditions assuring maximal LSD recovery have been determined, as well as the constant and proportional bias of the extraction procedure elaborated.