Effect of Mindful Hypnotherapy on Psychological Distress: A Systematic Review and Meta-Analysis.
Victor Julián Padilla, Vanessa Muñiz, Katherine Scheffrahn, Gary Elkins
Behavioral sciences (Basel, Switzerland) January 13, 2026 DOI: 10.3390/bs16010107 via PubMed
Summary
AI-generated from the abstractA systematic review and meta-analysis of five randomized controlled trials found that mindful hypnotherapy—an intervention combining hypnotic induction with mindfulness suggestions—produced large reductions in psychological distress (effect size 0.61) and stress (0.75), and a large increase in mindfulness (1.38) compared to waitlist and active control groups. The authors recommend future research on a wider range of clinical problems, use of active controls, measures of hypnotizability, and studies with diverse populations.
Study at a glance
| Characteristics | Systematic review and meta-analysis Randomized Peer reviewed |
|---|---|
| Sample size | 5 |
| Population | Adults |
| Intervention | Mindful hypnotherapy |
| Topics | Meditation |
| Keywords | Hypnosis Psychological distress |
| Key finding | Mindful hypnotherapy had a large effect on reducing psychological distress and stress and on increasing mindfulness compared to control groups. |
Abstract
Mindful hypnotherapy is an intervention that integrates hypnotic induction and direct suggestions (hypnosis) to increase mindfulness and reduce distress. In the present study, a systematic review and meta-analysis were conducted to investigate the effects of mindful hypnotherapy on psychological distress and mindfulness in adults. Further, the study evaluated the methodological quality of the included studies. A total of five publications of randomized controlled trials were identified. This meta-analysis found that, when compared to both waitlist and active control groups, mindful hypnotherapy had a large effect on the reduction in psychological distress (Hedges' g = 0.61, 95% CI [0.10, 1.12], z = 2.36, p = 0.0188) and stress (Hedges' g = 0.75, 95% CI [0.34, 1.16]; z = 3.58, p = 0.0003). Further, results also found mindful hypnotherapy had a large effect on increasing mindfulness (Hedges' g = 1.38, SE = 0.28; 95% CI [0.83, 1.92]; z = 4.9146, p < 0.001). Recommendations include conducting research examining mindful hypnotherapy in a wider range of clinical problems (i.e., generalized anxiety disorder, depression, post-traumatic stress). In addition, clinical trials of mindful hypnotherapy should include active controls and measures of hypnotizability. Further research is also needed with diverse populations.