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Effect of Mindful Hypnotherapy on Psychological Distress: A Systematic Review and Meta-Analysis.

Victor Julián Padilla, Vanessa Muñiz, Katherine Scheffrahn, Gary Elkins

Behavioral sciences (Basel, Switzerland) January 13, 2026 DOI: 10.3390/bs16010107 via PubMed

Summary

AI-generated from the abstract

A systematic review and meta-analysis of five randomized controlled trials found that mindful hypnotherapy—an intervention combining hypnotic induction with mindfulness suggestions—produced large reductions in psychological distress (effect size 0.61) and stress (0.75), and a large increase in mindfulness (1.38) compared to waitlist and active control groups. The authors recommend future research on a wider range of clinical problems, use of active controls, measures of hypnotizability, and studies with diverse populations.

Study at a glance

Characteristics Systematic review and meta-analysis Randomized Peer reviewed
Sample size 5
Population Adults
Intervention Mindful hypnotherapy
Topics Meditation
Keywords Hypnosis Psychological distress
Key finding Mindful hypnotherapy had a large effect on reducing psychological distress and stress and on increasing mindfulness compared to control groups.

Abstract

Mindful hypnotherapy is an intervention that integrates hypnotic induction and direct suggestions (hypnosis) to increase mindfulness and reduce distress. In the present study, a systematic review and meta-analysis were conducted to investigate the effects of mindful hypnotherapy on psychological distress and mindfulness in adults. Further, the study evaluated the methodological quality of the included studies. A total of five publications of randomized controlled trials were identified. This meta-analysis found that, when compared to both waitlist and active control groups, mindful hypnotherapy had a large effect on the reduction in psychological distress (Hedges' g = 0.61, 95% CI [0.10, 1.12], z = 2.36, p = 0.0188) and stress (Hedges' g = 0.75, 95% CI [0.34, 1.16]; z = 3.58, p = 0.0003). Further, results also found mindful hypnotherapy had a large effect on increasing mindfulness (Hedges' g = 1.38, SE = 0.28; 95% CI [0.83, 1.92]; z = 4.9146, p < 0.001). Recommendations include conducting research examining mindful hypnotherapy in a wider range of clinical problems (i.e., generalized anxiety disorder, depression, post-traumatic stress). In addition, clinical trials of mindful hypnotherapy should include active controls and measures of hypnotizability. Further research is also needed with diverse populations.

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