Tijdschrift voor Geneeskunde

ISSN 0371-683X

2 papers in the library · publishing 2023

Papers

Klassieke psychedelica: veiligheid, neveneffecten en medicatie-interacties

Tijdschrift voor Geneeskunde July 24, 2023 E. Geleyn, Kim P. C. Kuypers, Mathieu Seynaeve et al.

Classic psychedelics are non-addictive and have low toxicity, and their use under controlled conditions reduces the risk of serious unwanted effects such as persistent psychotic symptoms, disabling flashbacks, or increased suicidality. However, under uncontrolled conditions and without psychological support, these risks are real, and using these drugs to treat psychological symptoms should be strongly discouraged. Physicians should have open conversations with patients to inform them and assess risks, including possible interactions with other medications, which should be evaluated individually based on the medication and type of psychedelic.

DOI: 10.47671/tvg.79.23.049 Psychiatry Conversation Psychotherapist Psychology +1

Lachgas: om te lachen?

Tijdschrift voor Geneeskunde July 11, 2023 M. Cleerens, V. Leenaerts, S. Verelst

Recreational use of nitrous oxide, a legal and readily available gas, is increasingly popular among young people and poses serious medical risks. Unlike medical use where it is mixed with oxygen, recreational inhalation can cause acute hypoxia leading to coordination disorders, loss of consciousness, and headache. Chronic use results in myelo- and neuropathy from functional vitamin B12 deficiency, with motor weakness, gait ataxia, and sensory abnormalities affecting the lower limbs more than upper limbs. Diagnosis relies on history, clinical findings, MRI, and electromyography. Treatment includes vitamin B12, but stopping abuse is essential for recovery. Clinicians should actively inquire about nitrous oxide use when symptoms suggest it.

DOI: 10.47671/tvg.79.23.007 Medicine