Journal of neurology

ISSN 1432-1459

2 papers in the library · 24 citations · publishing 2024-2025

Papers

Improved quality of life and psychological symptoms following mindfulness and cognitive rehabilitation in multiple sclerosis and their mediating role for cognition: a randomized controlled trial.

Journal of neurology July 1, 2024 Ilse M Nauta, Maureen Van Dam, Dirk Bertens et al. 20 citations

Mindfulness-based cognitive therapy (MBCT) significantly enhances quality of life for individuals with multiple sclerosis (MS). In a trial involving 99 patients, MBCT improved depressive symptoms (Cohen's d = -0.46) and mental well-being (d = -0.73) at post-treatment, with mindfulness skills showing lasting effects even six months later (d = 0.42). Cognitive rehabilitation therapy (CRT) also reduced depressive symptoms (d = -0.46) but lacked long-term benefits. Both therapies positively impacted self-reported cognitive issues, highlighting their importance in managing MS-related psychological challenges.

DOI: 10.1007/s00415-024-12327-y Full text Mindfulness Cognitive rehabilitation Multiple sclerosis Quality of life

Predicting delirium in acute ischemic stroke: the PREDELIS score.

Journal of neurology May 11, 2025 Natalie Berger, Diether Kramer, Michael Schrempf et al. 4 citations

Delirium is a common complication of acute ischemic stroke and is linked to poor outcomes. A new risk score, PREDELIS, was developed using data from 14,475 stroke patients admitted to five Austrian stroke units between 2013 and 2021. Eight factors available at hospital admission predicted delirium: previous delirium, chronic alcohol use, age over 70, male sex, infection, high stroke severity, non-lacunar stroke type, and vision or hearing impairment. The score achieved moderate predictive accuracy, with patients scoring 5 or fewer points having a 2.5% risk of delirium, while those scoring 9 or more had a 30.9% risk. The tool can help clinicians identify high-risk patients for targeted prevention.

DOI: 10.1007/s00415-025-13073-5 Full text Acute ischemic stroke Prediction score Stroke care Delirium prevention +3