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Critical Care

ISSN 1364-8535

3 papers in the library · 123 citations · publishing 2010-2023

Papers

The effect of carbon dioxide on near-death experiences in out-of-hospital cardiac arrest survivors: a prospective observational study

Critical Care April 8, 2010 Zalika Klemenc–ketiš, Janko Kersnik, Štefek Grmec 82 citations

About 21% of cardiac arrest survivors report near-death experiences (NDEs). Higher levels of carbon dioxide (CO₂) in exhaled breath and arterial blood, as well as higher serum potassium, were linked to more frequent and intense NDEs. A logistic regression model accounting for 46% of the variance identified elevated CO₂ as an independent predictor of NDE occurrence; a linear regression model explained 34% of the variance in NDE scores, with higher CO₂, higher potassium, and prior NDEs as independent predictors. These associations had not been previously reported.

Incidence of near-death experiences in patients surviving a prolonged critical illness and their long-term impact: a prospective observational study

Critical Care February 27, 2023 A. Rousseau, Laurence Dams, Quentin Massart et al. 26 citations

Among 126 patients with prolonged ICU stays, 15% reported a near-death experience (NDE) as measured by the Greyson scale. Mechanical ventilation, sedation, analgesia, reason for admission, primary organ dysfunction, and dissociative and spiritual propensities were associated with NDE in initial analyses, but only dissociative and spiritual propensity strongly predicted NDE in a multivariate model. At one-year follow-up with 61 patients, NDE was not significantly linked to quality of life. The findings suggest that cognitive and spiritual factors, rather than medical parameters, are the main predictors of NDE recall in the ICU.

Hypercapnia and hypokalemia in near-death experiences

Critical Care January 1, 2010 Bruce Greyson 15 citations

A commentary on a study linking hypercapnia and hypokalemia to near-death experiences (NDEs) urges caution. The original study found a correlation, but the commentary notes that hypercapnia may simply indicate better cardiac output and perfusion pressure, which reduces amnesia during cardiac arrest, making patients more likely to remember events and report NDEs. Contradictory evidence from other studies, including one finding lower carbon dioxide levels during NDEs and a prospective study of 63 cardiac arrest survivors finding no association, along with the small sample size and unclear link between blood and brain carbon dioxide levels, suggest the findings require further research.