Human Psychopharmacology Clinical and Experimental
March 1, 2012
Ornella Corazza, Fabrizio Schifano, Pierluigi Simonato et al.
157 citations
Methoxetamine, a dissociative drug related to ketamine, has a much longer duration of action and intensity of effects, and its availability on the web represents a new recreational trend. The analysis of online, non-peer-reviewed material carries methodological limitations. The online availability of information on novel psychoactive drugs like methoxetamine constitutes a pressing public health challenge, requiring better international collaboration and novel forms of intervention to address this fast-growing phenomenon.
Human psychopharmacology
May 1, 2017
Sulaf Assi, Nargilya Gulyamova, Paul Kneller et al.
35 citations
An analysis of 303 internet discussion forum threads reveals three main themes about cathinone use, effects, and toxicity. Users reported various intake methods depending on the derivative (mephedrone, 3-methylmethcathinone, methylenedioxypyrovalerone) and routes (eyeballing, insufflation, smoking, intravenous, oral, rectal, sublingual), along with multidrug use and purity concerns. Positive effects included increased energy, euphoria, and empathogenic feelings. Toxic effects affected the nervous system (anxiety, hallucinations, nervousness, paranoia), cardiovascular system (angina, myocardial infarction, tachycardia), skin (discolouration, itching, allergy), and renal system (difficulty urinating). Drug-drug interactions with stimulants, depressants, and hallucinogens were also reported. Forums offer useful safety information.