Unveiling the Psychedelic Journey: An Appraisal of Psilocybin as a Profound Antidepressant Therapy.
Molecular biotechnology January 1, 2025 Fatima Iftikhar Shah, Somia Shehzadi, Fatima Akram et al. 2 citations
Psilocybin, a natural hallucinogen found in certain mushrooms, shows potential therapeutic benefits for depression, a global health concern linked to suicide rates that is often difficult to treat with conventional drugs. Psilocybin alters mood, cognition, and perception by acting on serotonin receptors in the brain, and these shifts in consciousness may promote healing. This comprehensive review examines psilocybin's biosynthesis, mechanisms of action, therapeutic applications, and anti-depressive effects, aiming to advance psychiatric care and offer new hope for depression treatment.