Among U.S. adults who have ever used a hallucinogen, four distinct patterns of lifetime use emerge: a group primarily using psilocybin (16%), a larger group using both LSD and psilocybin (46%), a group mainly using ecstasy (23%), and a group using multiple hallucinogens (15%). Older age is associated with higher odds of being in the LSD/psilocybin class compared with the psilocybin-only class, and non-White participants have higher odds of being in the ecstasy class. These overlapping use patterns suggest that clinical trials and future policies should account for polysubstance hallucinogen experiences.
People who use opioids and participate in online Reddit communities for opioid recovery often report positive experiences with psychedelics, describing symptom relief for anxiety, depression, and PTSD, along with enhanced mood, inner peace, emotional healing, and shifts in perspective. These experiences were linked to reprocessing trauma and disrupting negative thought cycles, supporting long-term recovery by fostering emotional resilience and clarity. However, concerns about the risks of self-administered psychedelic use were noted. The findings are exploratory due to the unique sample and context of an internet forum.