The role of psilocybin in depressive disorders
Current Medical Research and Opinion August 23, 2024 Jadwiga Najib 1 citation
Psilocybin combined with psychotherapy shows promise for treating depressive disorders, including major depressive disorder and treatment-resistant depression. Controlled and uncontrolled clinical trials report immediate and sustained antidepressant and anxiolytic effects, with benefits lasting up to 12 months post-treatment. Psilocybin has a favorable safety profile, is well-tolerated, and has low abuse potential. It may offer a valuable option for patients with depression, including those with comorbid terminal cancer. Future research is needed to confirm these findings and explore the synergistic interaction between psilocybin and psychological support.