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Tong Wang

2 papers in the library · 2 citations · publishing 2022-2025

Papers

White matter integrity of default mode network after a 3-month aerobic dance program in patients with amnestic mild cognitive impairment: a secondary analysis of a randomized clinical trial.

Quantitative imaging in medicine and surgery March 3, 2025 Han Wu, Yi Zhu, Xi Yang et al. 2 citations

A 3-month aerobic dance program improved cognitive function and strengthened structural connections within the default mode network in older adults with amnestic mild cognitive impairment. Sixteen participants in the exercise group showed significant gains in global cognition, memory, and executive function compared to baseline, while the control group showed no change. The exercise group also had increased structural connections between the hippocampus and several temporal regions, as well as between the default mode network and the supplementary motor area. These connectivity changes correlated with better cognitive scores, suggesting that aerobic dance may enhance brain structure and memory in this population.

Brain Research Bulletin Special Issue: Brain-body communication in health and diseases Brain-spleen axis in health and diseases: a review and future perspective.

Brain Research Bulletin February 1, 2022 Yan Wei, Tong Wang, Lei Liao et al.

The spleen filters blood and supports the immune system. New evidence shows it also influences brain function in health and disease through immune modulation. In mice, systemic inflammation or chronic social defeat stress causes spleen enlargement (splenomegaly). The antidepressant arketamine can reverse both splenomegaly and depression-like behaviors in stressed mice. A direct brain-to-spleen pathway exists: neurons in the paraventricular nucleus and central amygdala regulate humoral immune defense. Vagal nerve signaling also contributes to brain-spleen communication. This review summarizes recent findings on the brain-spleen axis.