BMC complementary medicine and therapies
January 2, 2024
Sean Ferkul, Zena Agabani, Osamu Minami et al.
8 citations
A virtual Mantram Repetition Program—a brief, mindfulness-based, non-trauma-focused group intervention—was feasible, acceptable, and safe for adults with posttraumatic stress disorder and substance use disorder. Over 8 weeks, groups of 4–5 participants met via Webex for 90-minute sessions. Of 43 enrolled, 5 did not start and 8 dropped out, leaving 35 completers (81.4% retention). Treatment completion and retention exceeded 70%. Qualitative feedback highlighted the acceptability of the delivery method, informative materials, and gaining a practical mindfulness tool for symptom management. Further longitudinal trials comparing the virtual program to other interventions are needed.
Frontiers in neuroendocrinology
October 1, 2025
Justin Matheson, Danial Behzad, Christina Zakala et al.
5 citations
A systematic review of 29 studies found limited evidence that sex influences the acute cognitive effects of cannabis or THC in humans. Only 6 of 29 articles (20.7%), representing 8 of 216 cognitive outcomes (3.7%), reported sex differences. All six studies found greater cognitive impairment in female participants for at least one measure; one study also found greater effects in male participants, and one found divergent effects between sexes. No consistent patterns emerged by cognitive domain, route of administration, or dosing paradigm. Methodological heterogeneity across studies prevents firm conclusions, and future research should examine hormonal modulation of cannabinoid effects.
Psychopharmacology
March 1, 2026
Patricia Di Ciano, Sampson Zhao, Pamela Kaduri et al.
2 citations
Taking a low-dose cannabis edible (average 7.3 mg of THC) leads to measurable decreases in verbal learning and memory, specifically on two measures of a free recall task, 150 minutes after ingestion. No effects were found on visual attention or executive function as measured by the useful field of view and trail making tests. Subjective feelings of intoxication increased, but blood THC levels did not correlate with any cognitive performance changes. The results suggest that people who use relatively low doses of cannabis edibles may experience some cognitive decrements while feeling intoxicated.
Journal of addiction medicine
Dafna Sara Rubin-Kahana, Ahmed Nabeel Hassan, Bernard Le Foll
A young man developed posttraumatic stress disorder after a psychedelic experience induced by LSD and DMT, during which a repressed memory of childhood sexual abuse was recovered. This is the first reported case of PTSD onset following a psychedelic experience. The authors note that trauma history is common among people with substance use disorder and that medical staff should be aware of such irregular presentations.