Loving-kindness meditation (LKM) is associated with measurable changes in brain structure and function, particularly in regions linked to emotional regulation, empathy, and compassion. This systematic review of neuroimaging studies in long-term LKM practitioners found consistent evidence of altered activity and gray matter volume in areas such as the insula, anterior cingulate cortex, and prefrontal cortex. These brain changes correlate with enhanced prosocial emotions and emotional balance, suggesting that LKM may foster neuroplasticity supporting mental well-being. The findings imply potential clinical applications for conditions involving emotional dysregulation, though further research is needed to confirm therapeutic efficacy.
A survey of psychiatric patients at a community mental health center found that 62.4% were open to hallucinogenic psilocybin therapy and 60.4% to non-hallucinogenic forms. Patients with major depressive disorder preferred hallucinogenic therapy, while those with borderline personality disorder or post-traumatic stress disorder favored non-hallucinogenic options, possibly due to concerns about the intensity of hallucinogenic experiences. Individuals with substance use disorder showed greater acceptance of both forms than those without. The findings suggest societal stigma is not a major barrier to psilocybin therapy and that non-hallucinogenic forms may offer a more accessible option for some groups.