Antibody Gene Therapy Mitigates Adverse Immunological Effects of 3,4‐Methylenedioxymethamphetamine (MDMA) in Male BALB/c Mice
The FASEB Journal April 1, 2020 Chris Bolden, C. Tilley, Charles E Hay et al.
MDMA, a recreational drug often used at raves, has toxic effects beyond its positive feelings. In the body's periphery, it suppresses the immune system, making users more vulnerable to infection. In the central nervous system, it triggers a proinflammatory response involving glial cell activation and overproduction of cytokines, chemokines, and adhesion molecules. The authors suggest a treatment that could reduce these harmful effects would be beneficial.