A Systematic Review of Therapeutic Potential of Illicit Drugs: A Narrative Overview of How Cannabinoids and Psychedelics Can be Used in Medicine
Iranian Journal of Chemistry & Chemical Engineering December 7, 2025 Sajedeh Rabipour, Evan Abdolkareem Mahmood, Abdol Ghaffar Ebadi et al.
Psychedelic therapy shows great potential and is reemerging amid social transformations and demands in psychotherapy. An integrative literature review examined articles on psychedelics and cannabinoids published between 2000 and 2021. For psychedelics, 22 articles were analyzed from an initial 77. For cannabinoids, 235 articles were selected from 1,164. The United States produced the most publications, followed by Canada and Australia. The cannabinoid literature addresses beneficial and adverse health effects, consequences of cannabis legislation, and associations with various variables. There is a lack of research on cannabis' medicinal use regarding treatments, diseases, standardization, routes of administration, and doses, highlighting the need for more research.