Delayed changes in neural visinin-like calcium-binding protein gene expression caused by acute phencyclidine administration.
Journal of neural transmission. General section January 1, 1995 Y Kajimoto, O Shirakawa, T Kuno et al.
In rats, the drug phencyclidine (PCP), which produces a schizophrenia-like state, reduced the expression of a calcium-binding protein called NVP-1 in the nucleus accumbens by 42% after 24 hours. This finding suggests that changes in calcium-binding proteins may contribute to the brain pathology underlying PCP-induced psychosis and possibly schizophrenia.