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Małgorzata Koziarska-Rościszewska

1 paper in the library · publishing 2015

Papers

Rekreacyjne używanie leków dostępnych w odręcznej sprzedaży: odurzanie i doping mózgu

March 1, 2015 A. Piątek, Małgorzata Koziarska-Rościszewska, J. Zawilska

Recreational use of over-the-counter drugs is rising, especially among young people. Dextromethorphan (DXM) at doses of 1.5–7.5 mg/kg body mass induces stimulation, mood improvement, and motor impairment; above 7.5 mg/kg it produces dissociative effects. Adverse reactions are pronounced when DXM is taken with alcohol or substances affecting CYP2D6 metabolism. Some users develop psychological dependence and withdrawal, and long-term use may impair cognitive function. Abuse of Tantum Rosa (benzydamine), reported in Brazil, Poland, and Romania, causes visual hallucinations and flashbacks. Pseudoephedrine, an amphetamine-like stimulant, can produce euphoria, hallucinations, and psychosis, but greater health threats arise from its derivatives ephedrone and methamphetamine.