A systematic evidence map of the association between cannabis use and psychosis-related outcomes across the psychosis continuum: An umbrella review of systematic reviews and meta-analyses.
Psychiatry Research November 1, 2023 J. Groening, Emma Denton, Rimsha Parvaiz et al.
Cannabis use is associated with psychotic-like experiences and schizotypal traits in healthy people, and with earlier onset and relapse of psychosis in patients with psychotic disorder. However, an association with clinical-high-risk states, attenuated symptoms, or transition to psychosis in high-risk populations could not be confirmed. Whether these associations are causal has not been adequately addressed in the evidence synthesis to date. This umbrella review evaluated 32 systematic reviews and meta-analyses, assessing their quality with the AMSTAR-2 tool.