Two cases of severe intoxication associated with analytically confirmed use of the novel psychoactive substances 25B-NBOMe and 25C-NBOMe
Clinical Toxicology January 1, 2014 M. H. Y. Tang, C. K. Ching, M. S. H. Tsui et al. 93 citations
Two men, aged 17 and 31, became acutely ill after taking drugs labeled 'NBOMe' or 'Holland film'. They experienced confusion, agitation, high blood pressure, rapid heart rate, fever, sweating, and dilated pupils, with some also having seizures, muscle breakdown, and abnormal liver function. Treatment required benzodiazepines and other medications. Urine analysis detected 25B-NBOMe in both patients and 25C-NBOMe in one. NBOMe compounds strongly activate serotonin and adrenaline receptors, explaining the symptoms. Clinical testing for these drugs is not widely available, so clinicians and laboratory staff are key to detecting these dangerous substances.