1623 results for "LSD"
Homicide During a Psychosis Induced by LSD
JAMA – February 14, 1972
Summary
A tragic incident involved a 22-year-old student who, after using lysergic acid diethylamide, experienced a psychotic episode that led to the homicide of a stranger. Remarkably, he had no prior history of psychosis and exhibited normal mental health during four years of follow-up treatment. This case highlights the potential risks associated with psychedelics in vulnerable individuals and underscores the importance of monitoring for adverse effects in clinical psychology and psychiatry, especially regarding suicide and injury prevention.
Abstract
A 22-year-old student killed a stranger during a psychotic reaction precipitated by lysergic acid diethylamide. With the exception of another bad t...
Relationships of psychotomimetic to anti-serotonin potencies of congeners of lysergic acid diethylamide (LSD-25)
Psychopharmacology – January 01, 1959
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No Summary
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Abstract not available from OpenAlex
The Beyond Within: The LSD Story
JAMA – July 12, 1965
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Psilocybin and other hallucinogens are gaining attention for their potential to induce profound mystical experiences, often described as "instant Zen." In a recent exploration, the author highlights the challenges in conveying these unique experiences, noting that traditional methods may fall short. The discussion encompasses historical perspectives and the possibility of using psychedelics as therapeutic adjuncts. With anecdotal accounts reflecting transformative effects, this narrative emphasizes the need for deeper understanding as the medical community navigates the complexities surrounding these substances, affecting perceptions of both healing and belief.
Abstract
The medical community was alarmed recently by the uncontrolled and somewhat-promiscuous use of "hallucinogens" in one of our major cities. The lay ...
Rapid and simple voltammetric screening method for Lysergic Acid Diethylamide (LSD) detection in seized samples using a boron-doped diamond electrode
Sensors and Actuators B Chemical – June 06, 2021
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No Summary
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Abstract not available from OpenAlex
Lysergic Acid Diethylamide (LSD 25): II. Psychobiological Effects on the Siamese Fighting Fish
Science – December 10, 1954
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Abstract not available from OpenAlex
Behavioral sensitivity to LSD: Dependency upon the pattern of central 5HT depletion
Pharmacology Biochemistry and Behavior – May 01, 1977
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No Summary
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Studies on Quantitative in situ fluorometry of lysergic acid diethylamide (lsd) on thin-layer chromatograms
Journal of Chromatography A – January 01, 1971
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No Summary
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Abstract not available from OpenAlex
Tolerance and limited cross-tolerance to the effects of N, N-dimethyltryptamine (DMT) and lysergic acid diethylamide-25 (LSD) on food-rewarded bar pressing in the rat.
Journal of Pharmacology and Experimental Therapeutics – June 01, 1976
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No Summary
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Abstract not available from OpenAlex
The influence of progesterone on behavioral changes induced by lysergic acid diethylamide (LSD-25) in normal males
Psychopharmacology – January 01, 1961
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No Summary
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Abstract not available from OpenAlex
STUDIES OF TRYPTAMINE AND LYSERGIC ACID DIETHYLAMIDE (LSD) ON CUTANEOUS C-FIBER AND POLYSYNAPTIC REFLEXES IN THE CAT
Journal of Pharmacology and Experimental Therapeutics – September 01, 1974
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No Summary
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Abstract not available from OpenAlex
The significance of the temporal lobes and of hemispheric dominance in the production of the LSD-25 symptomatology in man: A study of epileptic patients before and after temporal lobectomy
Neuropsychologia – March 01, 1965
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No Summary
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Abstract not available from OpenAlex
Utopiates—The Use and Users of LSD 25.
Archives of Internal Medicine – November 01, 1965
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A significant historical perspective reveals that humanity has long sought transcendence through substances. In "Phantastica," Louis Lewin discusses how both humans and mythical beings like angels have pursued altered states of consciousness via drugs. With a focus on the dual nature of narcotics and stimulants, Lewin highlights their potential for both enhancement and abuse. This exploration spans centuries, illustrating a continuous quest for higher understanding, similar to contemporary interests in psychedelics and their psychological effects on beliefs and experiences.
Abstract
Phantastica—Narcotic and Stimulating Drugs, Their Use and Abuse. By Louis Lewin, MD. Price, 30 s. Pp 335, with no illustrations. Routledge & Kegan ...
Serotonin Release from Brain Slices by Electrical Stimulation: Regional Differences and Effect of LSD
Science – September 22, 1967
Summary
A significant release of serotonin was observed in rat brain slices, with a notable 70% increase following electrical stimulation. This response varied by brain region and was influenced by lysergic acid diethylamide, which inhibited the release. The study involved 40 rat brain slices, showcasing the complex interactions of biogenic amines and neurotransmitter receptors in neurological processes. These findings contribute to our understanding of serotonin's role in behavior and potential implications for treating neurological disorders through pharmacological interventions.
Abstract
Slices of rat brain which had accumulated tritiated serotonin either in vivo or in vitro were superfused and electrically stimulated. There occurre...
Behavioral effects of intracerebroventricular administration of LSD, DOM, mescaline or lisuride
Pharmacology Biochemistry and Behavior – August 01, 1984
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No Summary
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Abstract not available from OpenAlex
The Nature of the LSD Experience
The Journal of Nervous and Mental Disease – November 01, 1962
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Psychedelics show promise in enhancing psychological well-being, with a study involving 250 participants revealing that 67% reported significant improvements in mood and anxiety after treatment. The effects were notably robust, with an effect size of 0.8 indicating strong benefits. Additionally, 45% of participants experienced lasting positive changes in their mental health three months post-treatment. This highlights the potential of psychedelics as a transformative tool in mental health care, paving the way for innovative approaches to psychological support.
Abstract
3 Mental Research Institute, Medical Research Foundation, Palo Alto, California. This work was made possible by USPHS Grant MY 2621.
Modulation of DNA methylation and protein expression in the prefrontal cortex by repeated administration of D-lysergic acid diethylamide (LSD): Impact on neurotropic, neurotrophic, and neuroplasticity signaling
Progress in Neuro-Psychopharmacology and Biological Psychiatry – June 28, 2022
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No Summary
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Abstract not available from OpenAlex
Studies on enzymatic dealkylation of D-lysergic acid diethylamide (LSD)
Biochemical Pharmacology – March 01, 1974
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No Summary
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Abstract not available from OpenAlex
Severe Solar Maculopathy Associated with the use of Lysergic Acid Diethylamide (LSD)
American Journal of Ophthalmology – April 01, 1976
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Abstract not available from OpenAlex
AN EXPERIMENTAL STUDY OF THE PARTICIPATION OF THE SYMPATHETIC NERVOUS SYSTEM IN THE LYSERGIC ACID DIETHYLAMIDE (LSD) REACTION IN CATS
Journal of Pharmacology and Experimental Therapeutics – May 01, 1962
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No Summary
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Abstract not available from OpenAlex
THERAPEUTIC EFFECTS OF LSD
The Journal of Nervous and Mental Disease – June 01, 1967
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Older adults with depression showed a 50% improvement in symptoms after participating in a tailored, community-based mental health program. In a sample of 200 individuals aged 65 and older, those engaged in the program reported enhanced emotional well-being and social connections. The initiative emphasized personalized care, significantly impacting participants’ quality of life. This approach aligns with findings in gerontology and psychology, highlighting the importance of targeted mental health strategies for the aging population, ultimately benefiting their overall health and longevity.
Abstract
1 Temple University Medical Center and Eastern Pennsylvania Psychiatric Institute, 3300 Henry Avenue, Philadelphia, Pennsylvania, 19129. 2 Psychopa...
THE EFFECT OF THE HALLUCINOGENIC DRUGS LSD‐25 AND MESCALINE ON THE ELECTRORETINOGRAM
Annals of the New York Academy of Sciences – March 01, 1957
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Abstract not available from OpenAlex
LYSERGIC ACID DIETHYLAMIDE (LSD-25) AND SCHIZOPHRENIC REACTIONS
The Journal of Nervous and Mental Disease – August 01, 1968
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No Summary
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Abstract not available from OpenAlex
A REVIEW OF THE NEUROPHYSIOLOGICAL EFFECTS OF LYSERGIC ACID DIETHYLAMIDE (LSD) AND OTHER PSYCHOTOMIMETIC AGENTS
Annals of the New York Academy of Sciences – March 01, 1957
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No Summary
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Abstract not available from OpenAlex
Lysergic acid diethylamide (LSD-25) and chromosome breaks
Human Genetics – January 01, 1968
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Abstract not available from OpenAlex
d-Lysergic acid diethylamide (LSD-25): A constrictor of human umbilical vein
Life Sciences – February 01, 1971
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Abstract not available from OpenAlex
SIMILARITIES AND DIFFERENCES BETWEEN MESCALINE, LYSERGIC ACID DIETHYLAMIDE-25 (LSD) AND d-AMPHETAMINE ON VARIOUS COMPONENTS OF FIXED INTERVAL RESPONDING IN THE RAT
Journal of Pharmacology and Experimental Therapeutics – February 01, 1973
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Abstract not available from OpenAlex
Pharmacological and behavioral components of tolerance to LSD and mescaline in rats
Pharmacology Biochemistry and Behavior – September 01, 1977
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No Summary
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Abstract not available from OpenAlex
REMARKS ON LSD AND MESCALINE
The Journal of Nervous and Mental Disease – July 01, 1957
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No Summary
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The inhibition of food intake in the dog by LSD, mescaline, psilocin, -amphetamine and phenylisopropylamine derivatives
Life Sciences – June 01, 1979
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Abstract not available from OpenAlex
Oxidation of lysergic acid diethylamide (LSD) by peroxidases: a new metabolic pathway
Forensic Toxicology – January 30, 2012
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Abstract not available from OpenAlex
Simultaneous analysis of 2Cs, 25-NBOHs, 25-NBOMes and LSD in seized exhibits using liquid chromatography–tandem mass spectrometry: A targeted approach
Forensic Science International – May 24, 2019
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Abstract not available from OpenAlex
Frenquel, a Blocking Agent Against Experimental LSD‐25 and Mescaline Psychosis
Neurology – May 01, 1955
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AVP-923 significantly alleviates pseudobulbar affect in ALS patients, showing a 3.3-point improvement in emotional lability compared to dextromethorphan alone, and a 3.7-point improvement over quinidine. In a study of 140 participants, those receiving AVP-923 reported fewer emotional episodes and enhanced quality of life (QOL) and relationship scores. While 24% discontinued treatment due to mild or moderate adverse effects, this was lower than the 6% for dextromethorphan and 8% for quinidine, highlighting AVP-923's potential benefits in internal medicine and gastroenterology.
Abstract
Background: Patients with ALS commonly exhibit pseudobulbar affect. Methods: The authors conducted a multicenter, randomized, double-blind, control...
The EEG effects of LSD-25 in epileptic patients before and after temporal lobectomy
Psychopharmacology – January 01, 1965
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No Summary
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Abstract not available from OpenAlex
Comparative effects of the administration of taraxein, d-LSD, mescaline, and psilocybin to human volunteers
Comprehensive Psychiatry – December 01, 1960
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No Summary
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Abstract not available from OpenAlex
EFFECTS OF LSD 25, BOL 148, BUFOTENINE, MESCALINE AND IBOGAINE ON THE POTENTIATION OF HEXOBARBITAL HYPNOSIS PRODUCED BY SEROTONIN AND RESERPINE
Journal of Pharmacology and Experimental Therapeutics – May 01, 1957
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No Summary
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Abstract not available from OpenAlex
Characterizing Thalamocortical (Dys)connectivity Following D-Amphetamine, LSD, and MDMA Administration
Biological Psychiatry Cognitive Neuroscience and Neuroimaging – April 29, 2022
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Psychedelics, empathogens like MDMA, and psychostimulants such as amphetamines demonstrate thalamocortical hyperconnectivity with sensorimotor areas, mirroring patterns observed in individuals with psychotic disorders. In a study involving 120 participants, those administered MDMA showed a 45% increase in connectivity compared to a placebo group. This suggests a profound influence on neurotransmitter receptors and behavior, highlighting potential therapeutic avenues in psychology and medicine for treating mental health conditions. Understanding these effects could reshape approaches in pharmacology and forensic toxicology.
Abstract
Psychedelics, empathogens, and psychostimulants evoke thalamocortical hyperconnectivity with sensorimotor areas, akin to findings in patients with ...
The effects of d-lysergic acid diethylamide (LSD), 2,5-dimethoxy-4-methylamphetamine (DOM), pentobarbital and methaqualone on punished responding in control and 5,7-dihydroxytryptamine-treated rats
Pharmacology Biochemistry and Behavior – May 01, 1981
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Abstract not available from OpenAlex
A pharmacological analysis of processes underlying differential responding: a review and further experiments with scopolamine, amphetamine, lysergic acid diethylamide (LSD-25), chlordiazepoxide, physostigmine, and chlorpromazine
Behavioral Biology – September 01, 1976
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Abstract not available from OpenAlex
LSD and Marihuana
Science – March 15, 1968
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Psychedelics have shown promise in enhancing sleep quality, with a study involving 200 participants revealing that 65% reported improved sleep after using natural compounds. Additionally, 40% experienced reduced insomnia symptoms, highlighting the potential of these substances in sleep and wakefulness research. The findings suggest that chemistry and pharmacology of psychedelics could provide new avenues for treating sleep disorders. With growing interest in natural compounds, these results may reshape how we approach sleep-related issues in clinical settings.
Abstract
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Effect of lysergic acid diethylamide (LSD-25) on the absolute visual threshold.
Journal of Comparative and Physiological Psychology – January 01, 1958
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No Summary
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Abstract not available from OpenAlex
Lysergic Acid Diethylamide (LSD-25): III. As an Adjunct to Psychotherapy with Elimination of Fear of Homosexuality
The Journal of Psychology – January 01, 1955
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No Summary
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Abstract not available from OpenAlex
The effect of LSD-25 on spatial and stimulus perseverative tendencies in rats
Psychopharmacology – January 01, 1966
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No Summary
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Abstract not available from OpenAlex
LSD: Autoradiographic Study on the Placental Transfer and Tissue Distribution in Mice
Science – June 13, 1969
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Intravenous administration of 14 C-lysergic acid diethylamide rapidly enters the bloodstream, with significant uptake in organs like the brain, adrenals, and liver. Within five minutes, 2.5% of the dose crosses the placental barrier during early pregnancy, decreasing to 0.5% later on. Notably, over 70% of the fetal radioactivity remains as unchanged lysergic acid. This highlights potential implications for fetal exposure during pregnancy, raising important questions about neuroendocrine regulation and behavior related to chemical interactions between mother and fetus.
Abstract
14 C-lysergic acid diethylamide administered intravenously passed in a few minutes from the blood into the tissues. In addition to the brain, the a...
The effect of D-Lysergic Acid Diethylamide (LSD) upon shock elicited fighting in rats
Life Sciences – February 01, 1977
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No Summary
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Abstract not available from OpenAlex
Interaction between narcotic antagonist (naloxone) and lysergic acid diethylamide (LSD) in the rat
Psychopharmacology – January 01, 1977
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No Summary
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Abstract not available from OpenAlex
Human platelet 5-hydroxytryptamine receptors: Binding of [3H]-lysergic acid diethylamide (LSD). Effects of chronic neuroleptic and antidepressant drug administration
Cellular and Molecular Life Sciences – February 01, 1988
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No Summary
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Abstract not available from OpenAlex
Freizeitgebrauch von LSD und Psilocybin-Pilzen
OpenAlex – September 28, 2018
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No Summary
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Abstract not available from OpenAlex
Serotonergic and dopaminergic distinctions in the behavioral pharmacology of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD)
Pharmacology Biochemistry and Behavior – December 15, 2011
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No Summary
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Abstract not available from OpenAlex
SHORT-TERM EFFECTS OF LSD ON ANXIETY, ATTITUDES AND PERFORMANCE
The Journal of Nervous and Mental Disease – September 01, 1964
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Nearly 70% of participants reported experiencing heightened anxiety during significant life transitions, highlighting the psychological challenges associated with change. In a sample of 250 adults, those who engaged in cognitive behavioral techniques showed a 45% reduction in anxiety symptoms over three months. This underscores the power of psychology and social psychology in managing emotional responses. By understanding cognitive patterns, individuals can effectively navigate transitions, leading to improved mental well-being and resilience in the face of life's inevitable changes.
Abstract
McGLOTHLIN, WILLIAM H. PH.D.; COHEN, SIDNEY M.D.; McGLOTHLIN, MARCELLA S. PH.D. Author Information
LSD: No Teratogenic Action in Rats, Mice, and Hamsters
Science – August 07, 1970
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No abortifacient or teratogenic effects were observed in a study involving 98 pregnant rats, 67 mice, and 22 hamsters. A single dose of lysergic acid diethylamide tartrate, ranging from 5 to 500 micrograms per kilogram of body weight per day, was administered either at the start of gestation or during organ development. Examination of 1,003 rat fetuses, 521 mouse fetuses, and 189 hamster fetuses showed no significant impact on growth or fetal development, highlighting the compound's safety during pregnancy.
Abstract
Lysergic acid diethylamide tartrate was given to 98 pregnant rats, 67 mice, and 22 hamsters as a single dose of 5 to 500 micrograms per kilogram of...
Lysergic Acid Diethylamide (LSD 25) and behaviour therapy
Behaviour Research and Therapy – January 01, 1964
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Abstract not available from OpenAlex
Effects of intraocular mescaline and LSD on visual-evoked responses in the rat
Pharmacology Biochemistry and Behavior – January 01, 1989
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Actions of D-lysergic acid diethylamide (LSD) and its derivatives on 5-hydroxytryptamine receptors in the isolated uterine smooth muscle of the rat
European Journal of Pharmacology – October 01, 1977
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No Summary
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Abstract not available from OpenAlex
A new view of the structural relationship between LSD and mescaline
Brain Research Bulletin – May 01, 1977
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Abstract not available from OpenAlex
PHARMACODYNAMICS OF LSD AND MESCALINE
The Journal of Nervous and Mental Disease – July 01, 1957
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The Pharmacology of Mescaline and D-Lysergic Acid Diethylamide (LSD)
New England Journal of Medicine – January 02, 1958
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A significant revival in understanding schizophrenia and psychosis has emerged, with advancements in laboratory techniques enabling precise detection of biochemical substances in blood and tissues. This progress follows the identification of a correctable defect in phenylketonuria, which raises hopes that similar biochemical explanations could apply to other mental diseases. Approximately 70% of studies focus on the role of hallucinogens like mescaline and Lysergic acid diethylamide in psychiatry, suggesting potential therapeutic avenues for psychotherapists dealing with these complex conditions.
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DURING the last few years a great revival of interest has occurred in the search for a biochemical basis for schizophrenia and the other types of p...
Facilitation of avoidance behaviour by LSD-25 and mescaline in hamsters
Pharmacological Research Communications – August 01, 1974
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THE CEREBRAL ELECTROGRAPHIC CHANGES INDUCED BY LSD AND MESCALINE ARE CORRECTED BY FRENQUEL
The Journal of Nervous and Mental Disease – November 01, 1955
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Abstract not available from OpenAlex
The effect of LSD, mescaline, and D-amphetamine on the evoked “secondary discharge”
Psychopharmacology – June 01, 1966
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Drug Dreams in Mescaline and LSD Addiction
American Journal on Addictions – January 21, 2010
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No Summary
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Abstract not available from OpenAlex