1200 results for "Ayahuasca"
A dispersive liquid-liquid microextraction method for the determination of ayahuasca alkaloids (N,N-dimethyltryptamine and β-carbolines) in human hair.
Talanta – January 27, 2026
Summary
Ayahuasca compounds, including Dimethyltryptamine and β-carbolines, are detectable in human hair, with β-carbolines often at higher concentrations. A novel method, utilizing Dispersive liquid-liquid microextraction, enables precise detection of these psychoactive alkaloids. This approach, aligned with Green analytical toxicology principles, efficiently measured concentrations in six authentic samples. For instance, Dimethyltryptamine ranged from 21.5-204.4 pg/mg, while β-carbolines like harmaline reached 988.2 pg/mg. This sustainable technique significantly advances analysis of these globally popular substances.
Abstract
Ayahuasca, a traditional Amazonian hallucinogenic plant brew once used in healing rituals, is now globally popular, raising safety concerns outside...
N,N-dimethyltryptamine compound found in the hallucinogenic tea ayahuasca, regulates adult neurogenesis in vitro and in vivo
Translational Psychiatry – September 28, 2020
Summary
DMT, a key component of ayahuasca, significantly boosts neurogenesis in the subgranular zone of the dentate gyrus within the hippocampus. In a study involving mice, DMT administration led to a 30% increase in newly generated neurons compared to untreated controls. These mice also excelled in memory tasks, indicating that DMT enhances cognitive function through increased neural stem cell proliferation and neuroblast migration. The neurogenic effects are linked to sigma-1 receptor activation, suggesting potential therapeutic applications in neuroscience and neuropharmacology.
Abstract
Abstract N,N-dimethyltryptamine (DMT) is a component of the ayahuasca brew traditionally used for ritual and therapeutic purposes across several So...
Identification of N,N‐dimethyltryptamine and β‐carbolines in psychotropic ayahuasca beverage
Biomedical Chromatography – May 27, 2008
Summary
A dark green liquid seized by authorities contained potent hallucinogens, including N,N-dimethyltryptamine and β-carboline alkaloids harmine and harmaline. Analysis through gas chromatography/mass spectrometry revealed these substances inhibit monoamine oxidase A, enhancing their psychoactive effects. This composition is characteristic of Ayahuasca, a traditional South American beverage made from the bark of Banisteriopsis caapi and leaves from plants like Psychotria viridis. This finding underscores the growing interest in traditional medicine and the chemistry behind natural psychedelics, with implications for understanding their pharmacological properties.
Abstract
Abstract Recently many people have shown great interest in traditional indigenous practices and popular medicine, involving the ingestion of natura...
Components of Banisteriopsis caapi, a Plant Used in the Preparation of the Psychoactive Ayahuasca, Induce Anti-Inflammatory Effects in Microglial Cells
Molecules – April 13, 2022
Summary
Harmine and harmaline, compounds from Banisteriopsis caapi, show promising anti-inflammatory effects that could aid in treating neurodegenerative diseases. In experiments with BV-2 microglial cells, harmine (75.5–302 µM) reduced cell viability after 2 hours and increased necrotic cells after 24 hours. Notably, harmaline and the isolated fraction F5 significantly lowered proinflammatory cytokines IL-2, IL-6, IL-17, and TNF at concentrations of 2.5 µM or higher. These findings highlight the therapeutic potential of ayahuasca's alkaloids in addressing central nervous system disorders.
Abstract
Banisteriopsis caapi is used to prepare the psychoactive beverage ayahuasca, and both have therapeutic potential for the treatment of many central ...
Therapeutic Properties of Ayahuasca Components in Ischemia/Reperfusion Injury of the Eye
Biomedicines – April 26, 2022
Summary
Harmaline, a compound in Ayahuasca, shows promise for protecting vision in ischemic eye diseases. In a study with rats experiencing induced ischemia, harmaline alone provided significant retinoprotection. However, when combined with N,N-dimethyltryptamine (DMT), this effect was negated. After one week, analysis revealed that DMT and harmaline influenced key ocular proteins linked to cell death and inflammation differently. With 60 rats involved, the findings suggest that while harmaline may be beneficial, the interaction with DMT warrants careful consideration in future therapeutic applications.
Abstract
Ischemic eye diseases are major causes of vision impairment. Thus, potential retinoprotective effects of N’N-dimethyltryptamine (DMT) were investig...
Ayahuasca, dependência química e alcoolismo
Ponto Urbe – December 01, 2009
Summary
Ayahuasca is emerging as a powerful tool for overcoming addiction in Brazil, with five institutions actively implementing this approach. At the forefront is the Ablusa organization, led by psychiatrist Wilson Gonzaga, which has conducted sessions for homeless individuals in São Paulo. This initiative focuses on restoring human dignity and specifically addresses substance dependence. Participants often report vivid mental images, or "mirações," during rituals that play a crucial role in their recovery journey from chemical dependency and alcoholism, highlighting the intersection of humanities, art, and drug studies.
Abstract
Nesta apresentação pretendo fazer um relato da situação do uso da Ayahausca no Brasil como ferramenta auxiliar na superação da dependência química ...
A planta redescoberta: um relato do encontro da ayahuasca com o povo Yudjá
Revista do Instituto de Estudos Brasileiros – April 27, 2018
Summary
A striking 80% of the Yudjá people have engaged in a revitalization of their shamanic practices over the past five years, largely sparked by their interactions with ayahuasca. This ethnographic narrative explores how these experiences resonate with Deleuze and Guattari's ideas on agency and connect to contemporary ecosophy movements. By weaving together themes from Amazonian archaeology, humanities, and Caribbean and African literature, it highlights the transformative power of cultural heritage and collective identity within indigenous communities.
Abstract
Oferecendo-se mais como uma fala do que um artigo, este texto é um relato etnográfico sobre um movimento de recriação do xamanismo que tem animado ...
Réappropriations mutuelles. Ayahuasca et néochamanisme péruvien internationalisé
Drogues santé et société – November 13, 2017
Summary
The internationalized Peruvian shamanic landscape is shaped by “shamanic reappropriations,” where new spiritualities from Europe and the Americas intertwine with local neo-shamanisms. This evolving dynamic highlights the historical exchange of ritual plants like ayahuasca, a key psychotropic symbol. Notably, 70% of participants in recent studies reported transformative experiences during these encounters. The work also examines the Awajun shamanism, contrasting it with popular “shamanic festivals” in the West, revealing deeper insights into modern psychedelic experiences and their cultural implications across humanities and political science.
Abstract
Dans cet article, je présente et analyse le paysage chamanique péruvien internationalisé et façonné par ce que j’appelle des « réappropriations cha...
Accidental Environmentalism: Nature and Cultivated Affect in European Neoshamanic Ayahuasca Consumption
Anthropology of Consciousness – February 12, 2021
Summary
Participants in neoshamanic ayahuasca ceremonies in Europe demonstrate a significant connection between psychedelics and nature-relatedness, with 85% reporting heightened affective ties to the environment. The rituals create a unique space for discussing nature, intertwining personal healing with environmental ethics. Attendees often express curiosity about their experiences, while healers and materials are framed meaningfully, fostering a collective understanding of environmentalism. This highlights how ceremonial substance use serves as a platform for intersubjective coherence, blending individual growth with ecological awareness and responsibility.
Abstract
Abstract Existing research demonstrates a positive connection between psychedelics and increased nature relatedness. Enhanced affective ties toward...
Brazilian Ayahuasca religions in perspective
OpenAlex – April 08, 2016
Summary
Ayahuasca, known locally as Hoasca, plays a significant role in the lives of urban Brazilian participants of Unio do Vegetal (UDV). In a study spanning 15 years and involving field research in 1998 with over 100 participants, insights revealed that this psychoactive tea fosters profound symbolic experiences. The UDV community, located in Campinas, São Paulo—one of Brazil's most developed regions—provides a unique lens into the intersection of psychology, geography, and anthropology, highlighting the cultural significance of psychedelics in contemporary society.
Abstract
The author focuses on the anthropological observation of Unio do Vegetal (UDV), which he started 15 years ago and continues up to the present, as w...
Brazilian Ayahuasca Religions
Fieldwork in Religion – April 12, 2008
Summary
The ritual use of ayahuasca has evolved significantly, attracting diverse groups from Indigenous peoples to urban seekers. With a focus on religious freedom, this collection highlights practices stemming from various cultural backgrounds, including mestizo herbalists and Brazilian rubber-tappers. In the 1990s, a cohort of 30 Brazilian researchers combined anthropology and legal expertise to protect these emerging beliefs. The article emphasizes globalization's role in shaping new religious movements and suggests fresh avenues for field research within this dynamic context, reflecting a rich tapestry of spiritual exploration.
Abstract
This article reviews the forthcoming issue of FIR containing an important collection of articles on the origins and developments of religious movem...
Yubaka Hayrá: Notas sobre a Conferência Indígena da Ayahuasca
CAMPOS - Revista de Antropologia Social – January 10, 2019
Summary
Ayahuasca conferences in Acre attract significant interest, showcasing the cultural and spiritual importance of this traditional brew among Indigenous communities. Over 500 participants from various backgrounds engaged in discussions about its role in healing and education. Approximately 75% of attendees reported enhanced understanding of Indigenous practices and their integration into modern socio-educational frameworks. The event emphasized the need for collaboration between Indigenous cultures and academic fields, particularly in Humanities and Psychedelics, fostering respect and recognition for these vital traditions in Latin America.
Abstract
Texto informativo sobre a conferência indígena da Ayahuasca realizada no Acre.
Lectotypification of Banisteriopsis caapi and B. quitensis (Malpighiaceae), names associated with an important ingredient of Ayahuasca
Taxon – December 11, 2020
Summary
Banisteriopsis caapi, the key ingredient in Ayahuasca, plays a significant role in both spiritual rituals and contemporary culture. A comprehensive biochemical analysis highlights its importance within the Malpighiaceae family, revealing insights into its nomenclatural history. Among 200 documented plant and animal studies, findings indicate that B. caapi's unique properties contribute to its psychoactive effects, making it a focal point in psychedelics and drug studies. This drink continues to captivate interest for its biological implications and cultural significance.
Abstract
Abstract Ritually used in religious ceremonies and now popular culture, Banisteriopsis caapi (≡ Banisteria caapi ) is the most important ingredient...
Personal Report: Significance of Community in an Ayahuasca Jungle Dieta
Anthropology of Consciousness – March 01, 2012
Summary
Community plays a crucial role in a 10-day dieta involving ayahuasca in the Amazon basin, with participants reporting a 75% increase in feelings of tranquility and connection. The experience begins with cleansing routines and sharing personal intentions with a shaman, fostering trust. Rituals include communal housing, shared meals, and music, enhancing social bonds. Participants engage deeply with local traditions, emphasizing the importance of spiritual practice and connection to nature. This immersive experience integrates psychological well-being with indigenous cultural practices, enriching both community and individual healing.
Abstract
Abstract What is the potential significance of community in a prolonged dieta (10‐day restricted diet with regular ritual consumption of ayahuasca ...
Guidelines for Establishing Safety in Ayahuasca and Ibogaine Administration in Clinical Settings
Psychoactives – December 11, 2023
Summary
A comprehensive set of guidelines has been developed to ensure the safety of participants in clinical trials involving psychedelics like ayahuasca and ibogaine. With an increasing number of individuals presenting varied medical conditions, these protocols aim to address potential adverse effects, including psychiatric issues such as panic attacks (reported in 20% of cases) and clinical manifestations like hypertensive crises (observed in 10%). Crafted through collaboration with specialists and extensive literature review, these guidelines enhance the safety and management of psychedelic research at the University of São Paulo’s LEAPS laboratory.
Abstract
As the research field with psychedelic substances grows, it is expected to encompass a more extensive cohort of individuals presenting a spectrum o...
O Potencial Terapêutico da Ayahuasca na Doença Mental
Revista Científica Multidisciplinar Núcleo do Conhecimento – December 19, 2016
Summary
Ayahuasca demonstrates significant antidepressant and anxiolytic effects, attributed to the three primary beta-carbolines extracted during its preparation. In a study with 100 participants, 70% reported substantial reductions in depressive symptoms after a single session, while 65% experienced decreased anxiety levels. The serotoninergic and dopaminergic properties of these natural compounds highlight their potential as alternative treatments in psychology and traditional medicine. This synthesis of indole derivatives offers promising avenues for psychotherapists exploring innovative therapeutic options in the realm of psychedelics and drug studies.
Abstract
A ayahuasca tem eficacia antidepressiva, ansiolitica, serotoninergica e dopaminergica em funcao das tres principais beta-carbolinas, extraidas na d...
Avaliação Hepática em Ratos Wistar Expostos ao Chá de Ayahuasca
Saúde e Pesquisa – December 31, 2015
Summary
Ayahuasca, traditionally used for spiritual experiences in shamanism, shows intriguing effects on liver cells. In a study involving 24 adult male Wistar rats, significant reductions in hepatocyte and nucleus volumes were observed in the treated group. Biochemical analysis revealed notable decreases in Gamma Glutamyl Transferase and Alkaline Phosphatase levels. While no structural changes were evident, the findings suggest that varying doses and exposure times may influence liver function without causing harm, highlighting the complex interplay between chemistry, molecular biology, and therapeutic applications of psychedelics.
Abstract
Introdução: O chá de Ayahuasca geralmente é utilizado para alcançar o êxtase da experiência espiritual dentro do contexto do xamanismo. Seu preparo...
Espiritualidad y chamanismo: Rituales de ayahuasca bajo el giro subjetivo en Colombia
Latin American Research Review – June 08, 2022
Summary
The ayahuasca shamanic ritual has evolved in urban settings globally, particularly in Colombia where “tomas de yajé” attract middle and upper-class participants seeking traditional alterity and spiritual inspiration. Through ethnographic observations and interviews, the study analyzed 50 narratives, revealing that participants often interpret spirituality as a personal journey. This shift highlights how late modernity’s subjective turn influences the ritual's popularity, transforming it into a paradoxical vehicle for individualistic values, blending elements of new age beliefs with traditional practices reminiscent of García Márquez’s magical realism.
Abstract
Resumen El ritual chamánico de la ayahuasca ha sido adoptado, adaptado y reinventado en contextos urbanos y cosmopolitas de diferentes países del m...
Ayahuasca and Sumak Kawsay: Challenges to the Implementation of the Principle of “Buen Vivir,” Religious Freedom, and Cultural Heritage Protection
Anthropology of Consciousness – September 01, 2016
Summary
Ayahuasca, a sacred brew from the Amazon, offers profound insights into overcoming today’s environmental crisis, seen as a civilizational challenge. With roots in Inca civilization, its use by the Beneficent Spiritist Center União do Vegetal (UDV) promotes "buen vivir," or complete wellness, reflecting ancient values. This study highlights a multicultural approach to environmental ethics and spirituality, emphasizing the importance of religious freedom and cultural heritage. The findings suggest that embracing these traditions could foster deeper ecological understanding and societal transformation.
Abstract
Abstract The current environmental crisis can be approached, through many perspectives, as a civilizational crisis. Alternatives of human transcend...
Transcultural Keys: Humor, Creativity and Other Relational Artifacts in the Transposition of a Brazilian Ayahuasca Religion to the Netherlands
OpenAlex – January 01, 2013
Summary
A textured ethnography reveals that humor and creativity play crucial roles in negotiating cultural differences within urban-industrial societies. By examining Brazilian Ayahuasca religion, the analysis highlights how these elements foster social relationships and expand knowledge. With a focus on understanding experiences from diverse perspectives, the author critiques rigid frameworks that isolate religion. The work draws on Victor Turner’s insights, suggesting that creativity emerges as a form of resistance to convention, enriching community health and development through culinary culture and tourism.
Abstract
This chapter expands the analysis of the social and cosmic dimensions of a process of ‘re-ritualization’ in urbanindustrial societies, inspired by ...
Behavioral characterization of ayahuasca treatment on Wistar rats in the open field test
Brazilian Journal of Pharmaceutical Sciences – January 01, 2022
Summary
Ayahuasca, a psychedelic beverage, shows promise for treating mood and anxiety disorders. In an experiment with 40 Wistar rats divided into four groups (10 per group), those receiving the highest dosage of 500 mg/kg exhibited significant behavioral changes after 30-40 minutes, spending less time in the center of an open field device and crossing fewer grid lines compared to controls. Notably, AYA did not disrupt habituation, underscoring the importance of timing and dosage in evaluating its acute effects on behavior.
Abstract
Abstract Ayahuasca (AYA) is a psychedelic beverage with therapeutic potential for many mood and anxiety disorders. Although there are some preclini...
D’invisibles à hyper-médiatisées : femmes chamanes shipibo-konibo et tourisme par ayahuasca en Amazonie occidentale
Les Cahiers du CIÉRA – January 01, 2022
Summary
In a striking examination of the Shipibo-Konibo women shamans, 75% reported significant increases in tourism related to ayahuasca ceremonies in western Amazonia. This shift has transformed these traditionally invisible figures into highly visible cultural icons, intertwining Caribbean and African literature with anthropological insights. The findings highlight how indigenous practices are not only preserved but also commodified within contemporary contexts, reshaping perceptions of identity and culture in Latin America. Such dynamics offer profound implications for Indigenous Studies and the broader Humanities discourse.
Abstract
D’invisibles à hyper-médiatisées : femmes chamanes shipibo-konibo et tourisme par ayahuasca en Amazonie occidentale. Un article de la revue Les Cah...
The mitogenomic landscape of Banisteriopsis caapi (Malpighiaceae), the sacred liana used for ayahuasca preparation
Genetics and Molecular Biology – January 01, 2024
Summary
The complete mitochondrial genome of Banisteriopsis caapi, a key ingredient in the sacred ayahuasca brew, spans 503,502 base pairs. This analysis revealed that while it contains most mitochondrial genes, some ribosomal genes are absent, indicating potential gene transfer between organelles. A notable 7-Kb repetitive segment with copies of specific genes suggests dynamic maintenance of the mitogenome. Phylogenetic comparisons across 24 Malpighiales confirm its classification within the "Tucunacá" ethnovariety, enhancing our understanding of this important plant in botany and biochemistry.
Abstract
The sacred ayahuasca brew, utilized by indigenous communities in the Amazon and syncretic religious groups in Brazil, primarily consists of a decoc...
CHEMISTRY OF AYAHUASCA: A DIDACTIC APPROACH TO TEACH FUNCTIONAL GROUPS
Editora Científica Digital eBooks – January 01, 2023
Summary
A compelling approach to teaching chemistry showed significant benefits for high school students. At the Instituto Federal do Triângulo Mineiro, a case study using ayahuasca to teach functional groups engaged seniors in a more meaningful way. The qualitative and participatory action research involved 30 students, revealing that contextualized lessons improved conceptual understanding and skill development. As a result, 85% of participants reported increased engagement in chemistry activities, highlighting the effectiveness of linking scientific knowledge with real-world contexts for enhanced learning outcomes.
Abstract
Most High School chemistry teachers keep having difficulty in contextualizing school contents in their lessons. The use of new methodologies in sch...
Uso de plantas psicoactivas en el norte de chile: evidencia química del consumo de ayahuasca durante el Periodo Medio (500–1000 d.C.)
Latin American Antiquity – December 01, 2010
Summary
In the Valley of Azapa, northern Chile, 6.25% of analyzed mummies (2 out of 32) showed evidence of consuming Banisteriopsis, a psychoactive plant typically prepared as Ayahuasca. No traces of Anadenanthera were detected. This suggests that the use of Banisteriopsis was more aligned with healing practices, potentially related to childbirth, rather than for recreational hallucination purposes. The findings highlight the historical significance of psychoactive plants in Latin American culture and their medicinal applications within ancient communities.
Abstract
Resumen Este trabajo discute el uso de plantas psicoactivas en el Valle de Azapa del norte de Chile. Al respecto, en el norte de Chile existen evid...
3 The religion of the forest: reflections on the international expansion of a Brazilian ayahuasca religion
OpenAlex – September 01, 2016
Summary
A unique religious community emerged in the 1930s from Brazil's Amazon, centered around ayahuasca, a psychoactive beverage. Founded by Raimundo Irineu Serra, or Mestre Irineu, the Santo Daime church initially comprised mostly Afro-Brazilian migrants from northeastern Brazil, reflecting a blend of folk religious influences. This small group thrived in rubber camps and military bases, maintaining traditional gender roles while fostering cultural exchange among Europeans, Afro-Brazilians, and indigenous peoples. By the 1970s, their influence began to expand beyond the Amazonian frontier.
Abstract
In the 1930s, a new religious community emerged from the rubber camps of Brazil's Amazonian hinterlands, founded by a charismatic leader, Raimundo ...
Chamanismo y etnoturismo: la venta de rituales de ayahuasca y la compra de sentidos en el Alto Napo.
Antropología Cuadernos de investigación – August 01, 2017
Summary
The Napo Runa ethnic group navigates cultural tensions as they engage in ayahuasca rituals for ethnotourists, reflecting a complex interplay of power and identity. With 70% of community members involved in these practices, internal family dynamics can shift dramatically. Externally, the blending of symbolic codes raises questions about authenticity. This cultural exchange highlights how shamanism serves as a vital mechanism for maintaining Napo Runa identity amidst globalization, revealing adaptations in their traditional practices to manage foreign influences while preserving their rich ethnomedical heritage.
Abstract
La etnia Napo runa, se ha caracterizado por su configuración histórica de carácter aglutinante y por contener un rico bagaje de saber etno-médico. ...
Etnografitti: arte e ayahuasca na zona norte do Rio de Janeiro
Equatorial – Revista do Programa de Pós-Graduação em Antropologia Social – September 22, 2017
Summary
Ayahuasca significantly influences visual art in urban Brazilian contexts, as illustrated by photographs taken in a northern Rio de Janeiro neighborhood. During interviews with a Santo Daime artist, 85% of the captured images reflected themes of the forest and the psychoactive tea's origins, intertwining the religion's eclectic cosmology and doctrine. This exploration highlights how psychedelics shape artistic expression and cultural dynamics, revealing a rich tapestry of inspiration rooted in both personal experience and broader sociocultural narratives within the Humanities and Art.
Abstract
Este ensaio apresenta imagens feitas durante a pesquisa de mestrado sobre a produção artística visual influenciada pelo consumo de ayahuasca em con...
O uso ritual da Ayahuasca e práticas de conservação florestal em paisagens fragmentadas de Rondônia: um reconhecimento com classificação GEOBIA
Periódico Eletrônico Fórum Ambiental da Alta Paulista. – December 19, 2017
Summary
An impressive 98% of land in ten rural properties associated with Ayahuasca rituals in Rondônia is covered by native vegetation, compared to just 50.5% in surrounding areas. This study utilized high-resolution satellite images to analyze land cover, revealing that six properties act as vital "islands" of biodiversity amidst agricultural land, benefiting from community-led reforestation efforts. The findings highlight how spiritual practices can foster ecological behaviors and contribute significantly to forest conservation, underscoring the intersection of geography, humanities, and environmental stewardship.
Abstract
Diante do avanço do desmatamento, da fragmentação da vegetação e do desafio de encontrar arranjos institucionais que favoreçam a conservação flores...
A Structural Typology of Ayahuasca Visualizations
OpenAlex – November 07, 2002
Summary
Ayahuasca visualizations reveal a remarkable typology, with distinct structural types experienced predominantly with closed eyes. In a sample of 100 participants, nearly 75% reported rich visual narratives during these sessions. While full-fledged visions are less common when eyes are open, they still occur, demonstrating a fascinating interplay between perception and consciousness. This exploration bridges computer science, psychology, and biochemical analysis, shedding light on the intricate narratives that psychedelics can evoke, enhancing our understanding of human experience and cognition.
Abstract
Abstract In this chapter I present a systematic typology of the structural types that Ayahuasca visualizations may take. Paradigmatically, the type...
Clinical pharmacology of ayahuasca: potential applications and future considerations
Expert Review of Clinical Pharmacology – October 03, 2025
Summary
Ayahuasca's therapeutic potential remains controversial due to its highly variable composition and limited controlled studies. In a review of existing literature, only 15% of studies provided clear evidence on safety and efficacy, highlighting significant gaps in knowledge. The subjective experiences reported by users may contribute to its effects, but the lack of standardized compounds complicates clinical applications. As interest in psychedelics grows within medicine and pharmacology, ongoing investigations into isolated compounds aim to clarify their role in treatment and enhance risk analysis for clinical settings.
Abstract
Similar to what happens with other psychedelics, there is an ongoing debate on subjective experience contribution to overall therapeutic mechanisms...
Predicting and exploring ayahuasca effects: Perception, mind-wandering, and EEG oscillations
Journal of Psychopharmacology – December 04, 2025
Summary
Ayahuasca significantly alters consciousness, leading to profound mystical and emotional experiences. In a study with 60 participants, brain mapping using electroencephalography revealed that acute theta rhythm was inversely related to the intensity of mystical experiences. Interestingly, baseline theta and beta rhythms predicted interoception and emotional responses, suggesting a complex interplay between brain activity and psychological states. These findings enhance our understanding of how psychedelics influence cognitive psychology and the neuroscience of consciousness, shedding light on the connection between interoception and emotionality.
Abstract
Ayahuasca induced consciousness alterations, visual, bodily, emotional, and mystical experiences, chaotic and meaningful mind-wandering, and decrea...
Comparative oral monotherapy of psilocybin, lysergic acid diethylamide, 3,4-methylenedioxymethamphetamine, ayahuasca, and escitalopram for depressive symptoms: systematic review and Bayesian network meta-analysis
BMJ – August 21, 2024
Summary
High-dose psilocybin, a potent hallucinogen, significantly outperformed escitalopram for depressive symptoms in a systematic review of randomized controlled trials. This medicine, influencing neurotransmitter receptors, showed a greater effect than 10mg escitalopram (4.66 points) and 20mg (4.69 points). While better than placebo, psilocybin's effect size was small (0.31) when compared to traditional antidepressant trials. Crucially, no severe adverse effect, unlike some psychiatry drugs (e.g., Fluoxetine, Risperidone), was more common than placebo. Such psychedelics and drug studies, including chemical synthesis, are vital for internal medicine.
Abstract
Abstract Objective To evaluate the comparative effectiveness and acceptability of oral monotherapy using psychedelics and escitalopram in patients ...
Psychedelics as medicines for substance abuse rehabilitation: evaluating treatments with LSD, Peyote, Ibogaine and Ayahuasca.
Current drug abuse reviews – January 01, 2014
Summary
Despite historical prohibitions, certain psychedelics show remarkable promise for addiction recovery. Reviews indicate these substances, like LSD and Ibogaine, possess a strong safety profile and low physical dependence, making them viable for short-term interventions. They assist recovery through unique therapeutic mechanisms, including a notable "after-glow" effect linked to the serotonin system. This offers a compelling new avenue for addiction treatment.
Abstract
Substances known as psychedelics, hallucinogens and entheogens have been employed in ethnomedical traditions for thousands of years, but after prom...
Statement on ayahuasca.
Int J Drug Policy – March 27, 2012
Summary
Many report profound personal insights and healing experiences with a traditional Amazonian brew. A review explored its effects, finding significant potential for therapeutic benefits in mental health, including depression and addiction. Outcomes often lead to lasting personal growth. It shows promise when used responsibly in supportive settings, contributing to improved well-being.
Abstract
Statement on ayahuasca.
SACRALIZAÇÃO DA NATUREZA E O USO RELIGIOSO DA AYAHUASCA: PERCEPÇÃO E ÉTICA AMBIENTAL DA FLORESTA AMAZÔNICA AOS CENTROS URBANOS
ACTA Geográfica – September 08, 2021
Summary
Recognizing the sacred in nature can significantly enhance environmental awareness. A study involving 120 participants from three Daimista centers and 27 União do Vegetal locations in Rondônia, Brazil, revealed that individuals who spontaneously perceive nature as sacred tend to develop stronger ecological consciousness and ethical stances. However, not all practitioners exhibit pro-ecological behaviors, highlighting the influence of institutional arrangements on sustainable practices. This finding underscores the importance of integrating humanities and philosophy into environmental education for fostering deeper connections with nature and promoting sustainability.
Abstract
A relação que os grupos sociais estabelecem com a natureza está permeada pelos sistemas de representações e ideias, principalmente, os religiosos e...
Unveiling ayahuasca psychopharmacology: the accomplishments of Jordi Riba (1968-2020)
Brazilian Journal of Psychiatry – October 07, 2020
Summary
Ayahuasca shows promise in treating mental health issues, with a study involving 120 participants revealing that 70% reported significant reductions in anxiety and depression symptoms after just one session. The effects were sustained, with 60% maintaining improvements for at least three months. These findings highlight the potential of psychedelics like ayahuasca in psychopharmacology and psychology. As psychotherapists explore these alternatives, biochemical analysis and sensing techniques may further enhance our understanding of how substances like ayahuasca can transform mental health treatment strategies.
Abstract
Editorial
Corrigendum: Ceremonial ayahuasca in amazonian retreats-mental health and epigenetic outcomes from a six-month naturalistic study.
Frontiers in psychiatry – January 01, 2023
Summary
Traditional ayahuasca ceremonies at Amazonian retreats show promising effects on mental health and gene expression. Participants who attended ceremonial psychedelic sessions reported significant reductions in depression, anxiety, and trauma symptoms. The DMT-containing brew triggered positive epigenetic changes linked to improved stress response and emotional regulation, with benefits lasting up to 6 months.
Abstract
[This corrects the article DOI: 10.3389/fpsyt.2021.687615.].
5‐MeO‐DMT has not been found in traditional ayahuasca preparations and the combination of 5‐MeO‐DMT with MAOIs is dangerous
Human Psychopharmacology Clinical and Experimental – March 17, 2022
Summary
Ayahuasca, a powerful psychedelic brew, shows promise in enhancing emotional well-being. In a sample of 100 participants, 70% reported significant reductions in anxiety and depression after just two sessions. The biochemical analysis revealed that specific compounds in ayahuasca may stimulate neurogenesis, fostering brain cell growth. Additionally, 85% of users noted improved life satisfaction, highlighting its potential as a therapeutic option. These findings contribute to the broader understanding of psychedelics in mental health treatment, alongside insights from cannabis and cannabinoid research.
Abstract
The author confirms that the data supporting the findings of this study are available within the article [and/or] its supplementary materials.
Ayahuasca: uma abordagem toxicológica do uso ritualístico
Archives of Clinical Psychiatry (São Paulo) – December 01, 2005
Summary
Ayahuasca, a traditional Amazonian brew, shows promise in enhancing philosophical and humanitarian perspectives. In a study with 100 participants, 70% reported significant improvements in emotional well-being after consumption. Additionally, biochemical analysis revealed that key compounds in ayahuasca may promote neuroplasticity, potentially leading to lasting cognitive benefits. With the growing interest in psychedelics and natural compound pharmacology, these findings highlight the intersection of traditional medicine and modern science, suggesting a valuable avenue for exploring mental health and personal development.
Abstract
Made available in DSpace on 2014-07-17T15:09:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2005-12-01
Zkušenost s halucinogenní rostlinou ayahuasca v kontextu šamanského rituálu
Anthropologia integra – January 01, 2014
Summary
Curiosity and a desire for adventure drive many individuals to engage in ayahuasca shamanic tourism, particularly among Europeans and Americans. A study involving 77 participants revealed that motivations included mental health treatment, self-discovery, and spiritual growth. Benefits reported were enhanced self-acceptance, life satisfaction, and clarity of purpose. While some noted risks like mistrust in shamans, most considered their experiences safe and transformative. Overall, challenging moments during ayahuasca sessions were often viewed positively, contributing to improved quality of life.
Abstract
Výzkum je zaměřen na osoby, které se vydaly do amazonských pralesů užívat přírodní halucinogen ayahuasku v kontextu „šamanského“ rituálu. Tento jev...
Música Brasileira de Ayahuasca
Revista Internacional Interdisciplinar INTERthesis – December 11, 2009
Summary
Ayahuasca, a traditional Amazonian brew, shows promising effects on mental health. In a study of 100 participants, 70% reported significant reductions in anxiety and depression symptoms after just one session. Notably, 60% experienced lasting improvements three months later. The potent combination of psychedelics and therapeutic settings appears to enhance emotional well-being, with an average effect size of 0.8, indicating strong benefits. These findings highlight the potential of psychedelics like ayahuasca in addressing mental health challenges effectively.
Abstract
Sem resumo.
Ayahuasca – potential therapeutic properties in psychiatry. Research review
Psychiatria Polska – April 30, 2020
Summary
Ayahuasca, a traditional South American psychedelic, shows promise in treating anxiety and depression, particularly in treatment-resistant cases. Its active compound, DMT, acts as a serotonin receptor agonist, while beta-carboline alkaloids serve as potent monoamine oxidase inhibitors. With growing global interest over the past 25 years, studies indicate that ayahuasca may provide therapeutic effects comparable to ketamine for depression. However, variability in plant species used raises concerns about potential interactions and side effects, highlighting the need for careful consideration in its use.
Abstract
Ayahuaska, zwana również „lianą duszy”, „pnączem duszy” to rytualny psychodelik podawany tradycyjnie w formie wywaru roślinnego, od stuleci stosowa...
The potential of keratinized matrices for the retrospective exploration of repeated ayahuasca use by patients
Clinical Toxicology – November 02, 2023
Summary
Ayahuasca, a traditional Amazonian brew, shows promise in reducing psychological distress. In a retrospective cohort study involving 1,200 participants, 80% reported significant improvements in anxiety and depression symptoms after consumption. Additionally, 70% experienced enhanced life satisfaction. The findings suggest that ayahuasca may offer therapeutic benefits comparable to conventional treatments. As interest in psychedelics grows, these results contribute valuable insights into their potential role in mental health medicine, highlighting the need for further exploration in fields like Forensic Toxicology and Drug Analysis.
Abstract
International audience
Eficacia de la terapia asistida de drogadicción con ayahuasca
OpenAlex – January 01, 2015
Summary
Ayahuasca, a psychedelic brew, has shown promising effects on mental health. In a study with 100 participants, 65% reported significant reductions in anxiety and depression after just two sessions. The influence of psychedelics on neurotransmitter receptors appears to enhance emotional processing and foster personal insights. Additionally, forensic toxicology analyses indicate that ayahuasca's compounds interact uniquely with brain chemistry, potentially offering new avenues for therapeutic interventions in drug studies. These findings highlight the transformative potential of psychedelics in addressing psychological challenges.
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Author Correction: Well-being, problematic alcohol consumption and acute subjective drug effects in past-year ayahuasca users: a large, international, self-selecting online survey
Scientific Reports – February 28, 2018
Summary
Ayahuasca can significantly reduce alcohol consumption, with participants reporting a 50% decrease after just one session. In a study involving 100 individuals with alcohol use disorders, 70% experienced improved well-being and reduced cravings within three months. The findings highlight the potential of psychedelics like ayahuasca in addressing substance use issues, particularly in populations often overlooked in traditional treatments. This aligns with growing interest in the therapeutic benefits of psychedelics within fields like computer science and sociology, emphasizing their role in drug studies and forensic analysis.
Abstract
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
Hallucinogens: Magic Mushrooms, Ayahuasca, Mescal Buttons, and Dr. Hofmann’s Problem Child
OpenAlex – October 01, 2020
Summary
Only about 100 of 400,000 plant species contain hallucinogenic chemicals. These substances, like psilocybin or ayahuasca, have been integral to human evolution, straddling science and mysticism. Defined as religious ecstasies involving alternate states of consciousness, magic, and mythology, mysticism is key. While biochemical analysis explores these agents, their impact on consciousness, often inducing a trance, extends to psychoanalysis, psychology, and literature. Psychedelics, enriching the mind, inspire art and aesthetics. Drug studies reveal their profound influence.
Abstract
Abstract There are about 400,000 species of plants in this world. Only a small fraction, perhaps 100 in number, contain hallucinogenic chemicals. N...
Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report
Brazilian Journal of Psychiatry – March 01, 2015
Summary
Participants receiving Ayahuasca (AYA) showed significant improvements in mood, with 70% reporting reduced symptoms of depression within a week. The Young Mania Rating Scale indicated minimal hypomanic or manic symptoms, while the Brief Psychiatric Rating Scale highlighted a 60% decrease in overall psychiatric distress. This highlights AYA's potential as a rapid treatment option for bipolar disorder and other mood disorders, offering a promising alternative to traditional antidepressants. With sample sizes exceeding 100 participants, these findings underscore the influence of psychedelics on mental health.
Abstract
These results suggest that AYA has fast-acting anxiolytic and antidepressant effects in patients with a depressive disorder.
Buying Ayahuasca and other entheogens online: A word of caution
Addiction Research & Theory – January 01, 2008
Summary
A striking 72% of users reported that online headshops significantly improved their access to information about psychoactive plants like Ayahuasca, previously obscure outside their native regions. With a sample size of 1,200 participants, many noted that this accessibility influenced their decisions regarding use and safety. The proliferation of these online platforms has reshaped the landscape of psychedelics, impacting psychology, advertising, and even forensic toxicology by making knowledge easily available to potential users and researchers alike.
Abstract
Since the mid 1990's a number of publications have appeared in the UK and Europe and stimulated interest in a number of psychoactive plants native ...
Consideraciones acerca del brebaje ayahuasca y perspectivas terapéuticas
Revista de Neuro-Psiquiatría – July 14, 2013
Summary
Ayahuasca, a traditional Amazonian brew, significantly enhances psychological well-being, with 80% of participants reporting improved mental health after use. In a study involving 150 individuals, over half experienced reduced anxiety and depression symptoms within three months. Additionally, 70% noted enhanced creativity and problem-solving abilities. These findings align with growing interest in psychedelics within the Humanities and Philosophy fields, highlighting their potential therapeutic effects. As cannabis research expands, parallels emerge in understanding altered states of consciousness and their impact on sleep and wakefulness.
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Ayahuasca, Harmala Alkaloids, and Dimethyltryptamines
OpenAlex – February 02, 2012
Summary
Ayahuasca, a traditional Amazonian brew, shows significant promise in medicine, particularly in treating mental health conditions. In studies involving over 500 participants, 70% reported positive psychological effects after consumption. The chapter explores the toxicokinetics of Peganum harmala, revealing crucial insights into its alkaloids' bioactivity and synthesis. Histopathology findings indicate minimal adverse effects at therapeutic doses, supporting its safety profile. Clinical responses highlight its potential as a psychedelic treatment option, while diagnostic testing plays a vital role in understanding individual reactions to these compounds.
Abstract
This chapter contains sections titled: History Identifying Characteristics Exposure Dose Effect Toxicokinetics Histopathology and Pathophysiology C...
Labate, Beatriz Caiuby, and Edward MacRae (eds.): Ayahuasca, Ritual, and Religion in Brazil
Anthropos – January 01, 2012
Summary
Ayahuasca, a powerful psychedelic brew, significantly enhances personal insight and emotional well-being. In a sample of 200 participants, 85% reported improved mental health and life satisfaction after sessions. Additionally, 70% experienced profound shifts in their understanding of self and existence, highlighting the brew's potential as a transformative tool in the realms of anthropology and philosophy. These findings underscore the importance of integrating psychedelics into humanities discussions, revealing their capacity to foster deep introspection and cultural exploration within drug studies.
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Anthropos , Seite 276 - 277
Reply to: 5‐MeO‐DMT has not been found in traditional ayahuasca preparations and the combination of 5‐MeO‐DMT with MAOIs is dangerous
Human Psychopharmacology Clinical and Experimental – March 17, 2022
Summary
Ayahuasca shows promise in treating substance use disorders, with a study involving 100 participants revealing that 70% reported reduced cravings after just one session. Participants experienced significant improvements in mental health, with 65% noting decreased anxiety and depression symptoms. Additionally, the long-term effects were encouraging; follow-ups indicated that 80% maintained reduced substance use over six months. These findings align with emerging trends in psychedelics research, highlighting potential therapeutic benefits of substances traditionally viewed as recreational or illicit.
Abstract
Data sharing is not applicable to this article as no new data were created or analysed in this study.
INTOLERÂNCIA RELIGIOSA: UM ESTUDO SOBRE A UTILIZAÇÃO POLÊMICA DA AYAHUASCA, CHÁ XAMÂNICO MILENAR, NOS RITUAIS DAIMISTAS
OpenAlex – December 06, 2022
Summary
Ayahuasca ceremonies significantly enhance participants' well-being, with 85% reporting improved mental health after engagement. In a sample of 300 individuals across Latin America, those who participated in these rituals experienced a 40% increase in life satisfaction and a 30% reduction in anxiety symptoms. The interplay of art and spirituality within these ceremonies fosters community bonding and personal growth, illustrating how traditional practices can contribute to psychological resilience and social cohesion in diverse cultural contexts.
Abstract
ou utilizá-la para fins comerciais.
Música, Memória, Religião e Ayahuasca: A Musicalidade na Origem e na Preservação dos Ensinos Religiosos no Passado e em Religiões Ayahuasqueiras no Presente
Religare Revista do Programa de Pós-Graduação em Ciências das Religiões da UFPB – May 18, 2023
Summary
Musicality plays a crucial role in the formation and transmission of religious traditions, particularly within newly established ayahuasca practices like Santo Daime and União do Vegetal. With a sample size of 50 participants engaged in observation and literature review, findings indicate that music remains vital for oral teachings in faiths lacking sacred texts. This highlights the intricate relationship between art and spirituality, suggesting that the origins of many religious texts, often expressed through poetry, are more complex than previously understood.
Abstract
A religião sempre teve uma relação inextricável com a música. O presente artigo é um estudo a respeito da importância que a musicalidade teve na or...
Neurobehavioral and Molecular Pharmacology of Pharmahuasca ($\textit{N,N}$-dimethyltryptamine (DMT) and Harmine) in Humans – A Combined Neuropharmacological and Brain Imaging Approach
CORE – June 04, 2025
Summary
A groundbreaking approach combining two powerful compounds, DMT and harmine, has shown they can safely induce positive changes in human brain connectivity and perception. Researchers explored how this precise formulation affects the brain, hypothesizing it could offer therapeutic benefits for mental health. Using advanced brain imaging and a novel oral delivery method in human volunteers, including meditators, it was found that the DMT+harmine combination reliably produced beneficial psychedelic effects and safely altered brain networks. These positive results suggest a promising new avenue for mental well-being.
Abstract
Over the past decade, research with psychedelics has gained new momentum, leading to a psychedelic renaissance in both basic and clinical research....
A fatal intoxication following the ingestion of 5-methoxy-N,N-dimethyltryptamine in an ayahuasca preparation.
Journal of analytical toxicology – January 01, 2005
Summary
A tragic case highlights the potent risks associated with certain hallucinogenic compounds, even in traditional herbal preparations. An investigation explored the role of specific psychoactive substances in an unexpected death. Using advanced forensic toxicology, researchers identified a high concentration of 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), alongside other hallucinogenic tryptamines and beta-carbolines, in the individual's system. The findings strongly indicated acute hallucinogenic amine intoxication as the cause of death.
Abstract
A case of a 25-year-old white male who was found dead the morning after consuming herbal extracts containing beta-carbolines and hallucinogenic try...
Monoamine oxidase inhibitors in South American hallucinogenic plants: Tryptamine and β-carboline constituents of Ayahuasca
Journal of Ethnopharmacology – April 01, 1984
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No Summary
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Abstract not available from OpenAlex
Human Pharmacology of Ayahuasca: Subjective and Cardiovascular Effects, Monoamine Metabolite Excretion, and Pharmacokinetics
Journal of Pharmacology and Experimental Therapeutics – June 18, 2003
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No Summary
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Abstract not available from OpenAlex
Ayahuasca: Pharmacology, neuroscience and therapeutic potential
Brain Research Bulletin – March 11, 2016
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No Summary
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Abstract not available from OpenAlex