The Future of Pain Management.
Pravarakhya Puppalla, Tara Menon Pattilachan, Rodrigo Salmeron de Toledo Aguiar, Charles E Argoff, Julie G Pilitsis
Neurologic clinics August 1, 2025 DOI: 10.1016/j.ncl.2025.04.007 via PubMed
Summary
AI-generated from the abstractPain is a complex experience involving sensory, emotional, and cognitive dimensions. A review of 3424 articles, narrowing to 143 relevant studies, shows progress in pain management through improved treatment algorithms, novel medications including ketamine, psychedelics, and cannabinoids, and innovative noninvasive neuromodulation techniques. The article outlines current practices and promising future research directions, emphasizing the potential for new interventions to address diverse causes of pain.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Keywords | Acute pain Chronic pain Pain intervention Pain management Pain: pain |
| Citations | 2 |
| Key finding | Progress in pain management includes advances in treatment algorithms, novel medications like ketamine, psychedelics, and cannabinoids, and noninvasive neuromodulation techniques. |
Abstract
This article explores the complexities of pain management, highlighting the multidimensional nature of pain, which encompasses affective, cognitive, and sensory experiences. The study examines the future of acute and chronic pain management through a thorough review of 3424 articles, ultimately including 143 relevant studies. Key findings indicate progress in treatment algorithms, novel medications (such as ketamine, psychedelics, and cannabinoids), and innovative approaches like noninvasive neuromodulation techniques. The article aims to outline current practices and exciting future research avenues, emphasizing the significant potential for new interventions in addressing the diverse causes of pain.