Novel Indole Derivatives as Serotonergic Psychedelic Agents for Treating Psychosis, Mental Illness, and CNS Disorders.
ACS medicinal chemistry letters June 12, 2025 DOI: 10.1021/acsmedchemlett.5c00309 via PubMed
Summary
AI-generated from the abstractA new class of indole derivatives has been developed as serotonergic psychedelic agents. These compounds, along with pharmaceutical compositions containing them, are intended for use in treating psychosis, mental illness, and other central nervous system disorders. The work also describes processes for preparing these novel compounds.
Study at a glance
| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Keywords | Brain conditions Neurological Psychiatric Psychosis Mental illness |
| Citations | 4 |
| Key finding | Novel indole derivatives have been developed as serotonergic psychedelic agents for treating CNS disorders. |
Abstract
Provided herein are novel indole derivatives as serotonergic psychedelic agents, pharmaceutical compositions, use of such compounds in treating psychosis, mental illness and central nervous system (CNS) disorders, and processes for preparing such compounds.