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Side effects of microdosing lysergic acid diethylamide and psilocybin: A systematic review of potential physiological and psychiatric outcomes

Stefan Modzelewski, Anna Stankiewicz, Napoleon Waszkiewicz, Kacper Łukasiewicz

Neuropharmacology March 7, 2025 DOI: 10.1016/j.neuropharm.2025.110402 via OpenAlex

Summary

AI-generated from the abstract

A review of psychedelic research finds that studies vary widely in how they report side effects and often follow participants for only a short time. The authors call for future work to describe side effects more clearly and systematically. This limitation makes it difficult to fully understand the risks associated with substances like psilocybin and LSD.

Study at a glance

Characteristics Review Peer reviewed
Topics LSD Microdosing Psilocybin
Keywords Adverse reactions Side effects Psychedelics hallucinogens
Citations 5
Key finding Heterogeneity in reporting side effects and short study durations limit current psychedelic research, and future studies should transparently and systematically present side effect descriptions.

Abstract

This review is limited by the heterogeneity in reporting side effects and the short duration of many studies. Future studies should transparently and systematically present a description of side effects.

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