Amanita muscaria and Amanita pantherina poisoning: two syndromes.
Andreja Vendramin, Miran Brvar
Toxicon : official journal of the International Society on Toxinology November 1, 2014 DOI: 10.1016/j.toxicon.2014.08.067 via PubMed
Summary
AI-generated from the abstractAmanita muscaria contains more excitatory ibotenic acid and less depressant muscimol than Amanita pantherina. Patients poisoned by A. muscaria were more often confused (26 out of 32) and agitated (20 out of 32) compared to those poisoned by A. pantherina (8 out of 17 confused, 5 out of 17 agitated). Patients poisoned by A. pantherina were more commonly comatose (5 out of 17) than those poisoned by A. muscaria (2 out of 32). The findings suggest the ibotenic or pantherina-muscaria syndrome may be divided into two subtypes based on the predominant mushroom species.
Study at a glance
| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Sample size | 49 |
| Population | Patients poisoned by Amanita muscaria or Amanita pantherina |
| Keywords | Agitation Amanita muscaria Amanita pantherina Coma Confusion |
| Key finding | Amanita muscaria poisoning more often causes confusion and agitation, while Amanita pantherina poisoning more often causes coma. |
Abstract
Amanita muscaria contains more excitatory ibotenic acid and less depressant muscimol compared to Amanita pantherina. In this study A. muscaria poisoned patients were more often confused (26/32, p = 0.01) and agitated (20/32, p = 0.03) compared to those poisoned with A. pantherina (8/17 and 5/17). Patients poisoned with A. pantherina were more commonly comatose (5/17) compared to those poisoned with A. muscaria (2/32) (p = 0.03). In conclusion, the so-called ibotenic or pantherina-muscaria syndrome might be divided into two subtypes.