[Psychopathology and differential diagnosis of so-called Cannabis psychoses].

Among 237 patients examined for drug-induced psychoses, 50 cannabis psychoses and 107 other drug-induced psychoses were compared with 219 schizophrenic patients. The cannabis psychoses showed general agreement in symptomatology with both other drug-induced psychoses and schizophrenia. The variation from schizophrenic symptoms was common to both cannabis and other drug-induced psychoses. The authors conclude there is no distinct disease "cannabis psychosis" or "drug-induced psychosis" as separate entities. While a slight drug-specific psychopathological undertone exists, it does not justify a syndromatic or nosological entity. The psychopathological cross section does not allow differentiation among the psychosis groups. The similarity may reflect either the same underlying pathological process or cannabis-triggered schizophrenia. The authors propose diagnosing symptomatic psychoses by considering etiology alongside syndrome diagnosis.

Study at a glance

Abstract

From 237 patients examined for drug-induced psychoses, 50 cannabis psychoses were examined according to the criterion "main cause of addiction" and 107 were examined according to the criterion "consumption during the last three months before hospitalization". The cannabis psychoses were compared to the other drug-induced psychoses as well as to a control group consisting of 219 schizophrenic patients. General agreement was found with the other drug-induced psychoses as well as with the group of schizophrenic patients. The variation from the symptomatology of the schizophrenics is generally common to both the cannabis psychoses and the other drug-induced psychoses. Judging by the results of our investigations, it must be concluded that there is no disease "cannabis psychosis" in its own right, just as the disease "drug-induced psychosis" also does not exist in its own right. While there is a certain slight drug-specific psychopathological undertone, it does not entitle us to speak of a syndromatic or indeed a nosological entity. The psychopathological cross section does not permit a differentiation in the individual psychoses groups mentioned, although this has often been attempted in the literature. That there are no relevant psychopathological differences between cannabis psychoses and endogenous schizophrenia could, for one, be based on the fact that we are observing the final stage of one and the same underlying pathological process. In this case both syndromes would in practice be endogenous psychoses, with the cause not being known in one case. The psychopathologic similarity of these two psychoses forms could, however, also be based on the assumption that cannabis psychoses are triggered schizophrenias, so that we could in both cases be dealing with one and the same disease. We see the solution to the problem of diagnosing symptomatic psychoses, and in particular cannabis psychoses, in making a diagnosis that takes the etiology into consideration in addition to the syndrome diagnosis.