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“So many relationships in the room”: Participant perspectives on the affordances and challenges of co-therapy in psychedelic assisted therapy

R. Ham, John Gardner, Adrian Carter, Paul Liknaitzky

September 26, 2025 preprint DOI: 10.31234/osf.io/4cn5r_v1 via OpenAlex

Summary

AI-generated from the abstract

In psychedelic-assisted therapy, two therapists often work together to support participants through preparation, dosing, and integration sessions. This qualitative study examined how participants experienced this cotherapy model within a trial of psilocybin-assisted therapy for generalized anxiety disorder. Interviews with 18 participants revealed three major themes: cotherapy on dose day provided safety, trust, and highlighted access issues; cotherapy influenced therapeutic processes; and cotherapy shaped the impact and credibility of therapeutic insights. Overall, participants valued cotherapy, which served both as a safety and supportive measure and as a potentiator of therapeutic processes. These findings can guide clinical practice and future research to enhance feasibility and accessibility while preserving safety and therapeutic benefits.

Study at a glance

Characteristics Qualitative study
Sample size 18
Population Participants in a trial of psilocybin-assisted therapy for generalized anxiety disorder
Intervention Psilocybin-assisted therapy
Topics Anxiety
Keywords Context archaeology Therapeutic relationship Affordance Perspective graphical
Key finding Participants generally valued cotherapy, which served as both a safety and supportive measure and a potentiator of therapeutic processes.

Abstract

Psychedelic-assisted therapy (PAT) frequently utilises a “cotherapy” model, in which two therapists jointly support participants or patients through preparation, dosing, and integration sessions. While common in clinical trials, the experience of cotherapy from the participant perspective remains underexplored. This qualitative study examined experiences of cotherapy within a trial of psilocybin-assisted therapy for generalised anxiety disorder. Semi-structured interviews with 18 participants (29 interviews in total) were analysed thematically, guided by Affordance Theory to consider how cotherapy dynamics shaped therapeutic possibilities. Three major themes were developed: (1) Dose day cotherapy: safety, trust and the realities of access; (2) Cotherapy influences therapeutic processes; (3) Cotherapy shapes the impact and credibility of therapeutic insights.Together, these findings position cotherapy in PAT as both a safety and supportive measure, and a potentiator of therapeutic processes. In the context of a single site with high levels of clinician qualification and training, participants generally valued cotherapy. Insights from this study can guide clinical practice and future research, so that feasibility and accessibility are enhanced while preserving the safety and therapeutic benefits afforded by cotherapy.

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