Psychedelics in the age of reproducibility: Reflections on aura, set and setting and the medicalization of mystical-type experiences.
Guy Simon, Nir Tadmor, Demian Halperin
The International journal on drug policy January 1, 2026 DOI: 10.1016/j.drugpo.2025.105074 via PubMed
Summary
AI-generated from the abstractPsychedelics can produce lasting changes in attitudes and behavior, with outcomes shaped by both the drug and the context of use ('set and setting'). As these substances move from traditional settings into clinical environments, a tension arises between authenticity and standardization. Drawing on Walter Benjamin's concept of 'aura,' this article examines what may be lost or gained when psychedelic experiences are reproduced in institutional settings. It explores how set and setting contribute to authenticity, analyzes the implications of medicalization, and considers the roles of ritual and commodification. The authors propose ways to integrate traditional context with clinical approaches to preserve psychedelics' transformative potential.
Study at a glance
| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Topics | Psychedelic-assisted therapy |
| Keywords | Medicalization Naturalistic psychedelic use Set and setting Therapeutic authenticity |
| Citations | 2 |
| Key finding | Applying Walter Benjamin's concept of 'aura' to psychedelic experiences reveals that removing them from original contexts and reproducing them in clinical settings may both diminish and preserve their transformative potential, depending on how set and setting are managed. |
Abstract
Psychedelics induce transformative experiences leading to lasting changes in attitudes and behaviour, with outcomes depending on both pharmacological factors and the context of the experience ('set and setting'), marking a paradigm shift in mental health treatment. As psychedelics transition from traditional contexts to clinical settings, tension emerges between authenticity and standardization. This article uses Walter Benjamin's concept of "aura" (The Work of Art in the Age of Mechanical Reproduction) to examine what may be lost or gained when psychedelic experiences are removed from original contexts and reproduced in institutional settings. We explore how set and setting contribute to authenticity, analyse medicalization's implications, examine the roles of ritual and commodification, and propose ways to integrate traditional context with clinical approaches to preserve psychedelics' transformative potential.