Exploring the importance of bodyset for the psychedelic experience and beyond
Malin Vedøy Uthaug, Giancarlo Allocca, Martha Havenith, Attila Szabo, Fernando Rosas, Johannes G. Ramaekers
Journal of Psychedelic Studies September 8, 2025 DOI: 10.1556/2054.2025.00418
Summary
AI-generated from the abstractThe paper introduces the concept of 'bodyset'—the state of the body, including both body and brain—as a vital element in preparing for psychedelic experiences, expanding the traditional 'set and setting' framework. Through a literature review, it argues that the body likely matters for wellbeing, peak performance, and peak experiences. Comprehensive multidisciplinary research, especially on biomarkers, is needed to clarify the role of bodyset in psychedelic experiences and therapy outcomes. The authors suggest that considering physical state alongside psychological and environmental factors may enhance understanding of psychedelic effects and inform other treatments like breathwork.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Citations | 1 |
| Key finding | The paper proposes that the physical state of the body (bodyset) is an important but underexplored factor in psychedelic experiences and therapy, warranting further research. |
Abstract
AbstractBackgroundResearch has shown that psychedelics may have therapeutic potential in treating mental disorders like depression and anxiety. However, the mechanisms and actions underlying their effects are still not fully understood. Similarly, while the significance of mindset and setting in shaping psychedelic experiences and therapeutic outcomes is well established, information about the influence of the body is comparatively scarce.AimThis paper introduces the concept of bodyset, defined as the state of the body, including both the body and brain. We suggest it as a vital element in preparing for psychedelic experiences and beyond, broadening the traditional ‘set and setting’ framework.MethodsThrough an extensive literature review, we demonstrate the likely importance of the body in wellbeing, peak performance and peak experiences.ResultsComprehensive multidisciplinary research, particularly focusing on various biomarkers, is needed to elucidate the potential role of bodyset in the psychedelic experience and therapy outcomes, and to guide future treatment approaches for mental health disorders.ConclusionOur exploration of the bodyset concept emphasizes the importance of considering not only psychological and environmental factors (mindset & setting), but also the physical state of the body in preparation for psychedelic experiences and psychedelic therapy. This holistic perspective may enhance our comprehension of their effects, therapeutic potential and inform the application of other treatment modalities, such as breathwork, in mental health care.