Advancements in Treating Psychiatric Disorders With Psilocybin

Psilocybin may help people with depression that does not respond to other treatments, producing effects that start quickly and last a long time. However, current psilocybin treatment requires many psychotherapy sessions, which can make it less available and more expensive. It is not yet known whether psilocybin works without this accompanying therapy. The long-term safety of psilocybin treatment also remains unclear.

Study at a glance

Abstract

Psilocybin shows promise for treatment-resistant depression, with rapid onset and long-lasting effects. Psilocybin treatment currently involves extensive psychotherapy sessions, which may limit accessibility and increase costs. The efficacy of psilocybin without concurrent psychotherapy is unknown. Long-term safety risks of psilocybin treatment remain uncertain.