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Postmarketing Safety Concerns With Esketamine: A Disproportionality Analysis of Spontaneous Reports Submitted to the FDA Adverse Event Reporting System

May 25, 2021 DOI: 10.64239/pi-qt2702

Summary

AI-generated from the abstract

Esketamine is more likely than venlafaxine to cause suicidal ideation, induce mania, and produce euphoric mood, indicating potential for abuse. Caution is warranted when using esketamine.

Study at a glance

Key finding Esketamine is more likely than venlafaxine to cause suicidal ideation, induce mania, and produce euphoric mood, suggesting abuse potential.

Abstract

Esketamine appears more likely than venlafaxine to cause suicidal ideation. Induction of mania was more common than with venlafaxine. Induction of euphoric mood suggests abuse potential. Caution is warranted.

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