Ketamine for Postpartum Depression: A Systematic Review
Jaylyn Thompson, David F. Lo, Alexis Foschini, Suvan Sundaresh, Don D. Shamilov
Research Posters May 2, 2024 DOI: 10.31986/issn.2689-0690_rdw.stratford_research_day.105_2024
Summary
AI-generated from the abstractA review of eight randomized controlled trials examined whether ketamine given during cesarean section can reduce postpartum depression. The evidence suggests ketamine may help prevent or lessen postpartum depression symptoms after C-section, though some studies found no significant effects. More research is needed to determine optimal dosing and to clarify the causal relationship between ketamine and postpartum depression in this context.
Study at a glance
| Characteristics | Systematic review Randomized Peer reviewed |
|---|---|
| Population | Women undergoing cesarean section |
| Intervention | Ketamine |
| Key finding | Ketamine may reduce postpartum depression symptoms after cesarean section, but some studies reported no significant effects and further research is needed. |
Abstract
The purpose of this review is to explore perinatal ketamine’s potential for reducing postpartum depression after cesarean section. Articles reviewed from Pubmed, Cochrane, and Web of Science using specific search terms. 8 final papers were used for review after excluding duplicates and irrelevant titles and abstracts. Ketamine showed potential in reducing postpartum depression symptoms post C-section, although some studies reported no significant effects. All studies were randomized control trials. Ketamine may help prevent or lessen postpartum depression symptoms post C-section, but more research is needed to understand dosing and its casual relationship with PPD in this context.