How ketamine helps to overcome depression
eLife December 12, 2014 DOI: 10.7554/elife.05418
Summary
AI-generated from the abstractKetamine can reduce depression symptoms by targeting NMDA receptors in the brain, as shown in experiments with genetically modified mice. The findings suggest a specific mechanism for the drug's rapid antidepressant effects.
Study at a glance
| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Genetically modified mice |
| Intervention | Ketamine |
| Citations | 1 |
| Key finding | Ketamine reduces depression symptoms by targeting NMDA receptors in the brain. |
Abstract
Genetically modified mice shed new light on how ketamine can target NMDA receptors in the brain to reduce the symptoms of depression.