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Peyote Alkaloids: Identification in the Mexican Cactus Pelecyphora aselliformis Ehrenberg

J.m. Neal, Patricia Sato, William N. Howald, Jerry L. Mclaughlin

Science June 9, 1972 DOI: 10.1126/science.176.4039.1131 via OpenAlex

Summary

AI-generated from the abstract

Alkaloid extracts from the Mexican peyote cactus Pelecyphora aselliformis Ehrenberg contain hordenine, anhalidine, pellotine, 3-demethyltrichocereine, mescaline, 3,4-dimethoxy-β-phenethylamine, and the N-monomethyl derivatives of mescaline and 3,4-dimethoxy-β-phenethylamine. This is the first report of mescaline and several other alkaloids occurring in a North American cactus outside the genus Lophophora.

Study at a glance

Characteristics Chemical analysis Peer reviewed
Topics Mescaline
Keywords Cactus Phenethylamine Traditional medicine Chemistry
Citations 16
Key finding Mescaline and several other alkaloids were identified for the first time in a North American cactus species other than Lophophora, specifically Pelecyphora aselliformis.

Abstract

Hordenine, anhalidine, pellotine, 3-demethyltrichocereine, mescaline, 3,4-dimethoxy-β-phenethylamine, and the N -monomethyl derivatives of mescaline and 3,4-dimethoxy-β-phenethylamine have been isolated or identified, or both, in alkaloid extracts of a Mexican "peyote" cactus, Pelecyphora aselliformis Ehrenberg. This is the first report of the occurrence of some of these alkaloids, including mescaline, in a North American cactus other than Lophophora .

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