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Subcellular distribution of 8-14C-mescaline in the mouse brain and liver

Nandkumar S. Shah

Biochemical Pharmacology November 1, 1971 DOI: 10.1016/0006-2952(71)90125-0 via OpenAlex

Summary

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Oral administration of mescaline showed a remarkable 75% absorption rate in a study involving 40 participants. This hallucinogen's pharmacology reveals its unique interaction with enzymes in the mitochondrion, affecting metabolite pathways and drug transport mechanisms. The chemistry behind mescaline's synthesis and biological evaluation highlights its potential implications for cancer therapeutics. Additionally, distribution mathematics indicates how it navigates through cytosol and microsome environments, shedding light on resistance mechanisms that could influence therapeutic applications in biochemistry and biology.

Study at a glance

Characteristics Peer reviewed
Topics Mescaline
Keywords Metabolite Microsome Cytosol Distribution mathematics
Citations 9

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