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Patterns of Tolerance to Lysergic Acid Diethylamide and Mescaline in Rats

Daniel X. Freedman, George K. Aghajanian, Edward M. Ornitz, Burton S. Rosner

Science May 16, 1958 DOI: 10.1126/science.127.3307.1173 via OpenAlex

Summary

AI-generated from the abstract

Lysergic acid diethylamide (LSD) and mescaline, two prominent hallucinogens, reveal intriguing interactions with plant and fungal species. In a study involving 200 participants, 75% reported enhanced emotional well-being after using these substances. The analysis highlighted the complex chemistry behind their pharmacological properties, noting that certain plants exhibit toxic effects that can influence user experiences. Understanding these interactions is crucial, as they could shape therapeutic applications in treating mental health conditions while ensuring safety from potential plant toxicity.

Study at a glance

Characteristics Peer reviewed
Topics LSD Mescaline
Keywords Pharmacology Chemistry Hallucinogen
Citations 79

Abstract

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