Neurocognitive impairments in MDMA and other drug users: MDMA alone may not be a cognitive risk factor
Karen L. Hanson, Mónica Luciana
Journal of Clinical and Experimental Neuropsychology September 30, 2009 DOI: 10.1080/13803390903042361 via OpenAlex
Summary
AI-generated from the abstractModerate MDMA use does not cause lasting cognitive impairments beyond those linked to general heavy drug use, but using multiple drugs together may lead to dose-related problems in temporal and frontoparietal brain function. Marijuana use appears especially harmful. The cause-effect relationships remain uncertain.
Study at a glance
| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Topics | MDMA |
| Keywords | Neurocognitive Cognition Drug Risk factor |
| Citations | 34 |
| Key finding | Moderate MDMA use does not produce persistent impairments beyond those from general heavy drug use, but polydrug use may cause dose-related temporal and frontoparietal dysfunction, with marijuana use being especially problematic. |
Abstract
This study and our previous report (Hanson, Luciana, & Sullwold, 2008) suggest that moderate MDMA use does not lead to persistent impairments above and beyond that associated with generally heavy drug use, but polydrug use may lead to dose-related temporal and frontoparietal dysfunction. Marijuana use may be particularly problematic. Cause-effect relations are unclear.