MDMA induced hyperthermia: a survivor with an initial body temperature of 42.9 degrees C.
Emergency Medicine Journal September 1, 1997 DOI: 10.1136/emj.14.5.336 via OpenAlex
Summary
AI-generated from the abstractA young man survived a body temperature of 42.9 °C after taking MDMA (Ecstasy). He experienced seizures, muscle breakdown, metabolic acidosis, and respiratory failure. Treatment with assisted breathing, aggressive fluids, early dantrolene, and cooling measures led to recovery. This is the first report of a survivor with such severe hyperthermia from MDMA.
Study at a glance
| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | Young male who ingested MDMA |
| Interventions | assisted ventilation aggressive fluid therapy dantrolene cooling measures |
| Topics | MDMA |
| Keywords | Medicine Rhabdomyolysis Dantrolene Anesthesia |
| Citations | 59 |
| Key finding | A young male survived severe hyperpyrexia (42.9 °C) after MDMA ingestion with treatment including dantrolene, aggressive fluids, and assisted ventilation. |
Abstract
A young male survived hyperpyrexia (42.9 degrees C) following MDMA ("Ecstasy") ingestion. He developed convulsions, rhabdomyolysis, metabolic acidosis, and respiratory failure. This was successfully managed by assisted ventilation, aggressive fluid therapy, and the early administration of dantrolene, in addition to cooling measures. This is the first report of a survivor with such a severe hyperpyrexia.