Memory impairment in abstinent MDMA ("Ecstasy") users
Karen I. Bolla, Una D. Mccann, George A. Ricaurte
Neurology December 1, 1998 DOI: 10.1212/wnl.51.6.1532 via OpenAlex
Summary
AI-generated from the abstractPeople who have stopped using MDMA show deficits in both verbal and visual memory. The severity of these memory problems is linked to how much MDMA they used in the past and to lower levels of serotonin activity in the brain, measured by a serotonin metabolite in spinal fluid.
Study at a glance
| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Population | Abstinent MDMA users |
| Topics | MDMA Serotonin |
| Keywords | Memory impairment Neurotoxicity |
| Citations | 376 |
| Key finding | Abstinent MDMA users have impairment in verbal and visual memory that correlates with the degree of MDMA exposure and reduction in brain serotonin. |
Abstract
Abstinent MDMA users have impairment in verbal and visual memory. The extent of memory impairment correlates with the degree of MDMA exposure and the reduction in brain 5-HT, as indexed by CSF 5-HIAA.