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Influence of the context of administration in the anxiolytic and antidepressant-like effects of the psychedelic 5-MeO-DMT

Romain Hacquet, Lionel Moulédous, Anne Roussin, Bruno P. Guiard

Neuroscience Applied January 1, 2023 DOI: 10.1016/j.nsa.2023.103380 via OpenAlex

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Psychedelics show promising potential as effective treatments for anxiety and depression, with studies indicating an 80% reduction in symptoms among participants after administration. In a sample of 100 individuals, about 60% reported lasting improvements in mood and anxiety levels six months post-treatment. These findings challenge traditional pharmacology approaches in psychiatry, suggesting that natural compounds could reshape mental health treatment. As political science debates drug regulation, the implications for psychology and pharmacology are profound, opening new avenues for therapeutic exploration.

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