No trip needed for psychedelics to lift mood?

LSD and psilocin, the active compounds in magic mushrooms, bind to the same molecular targets in the brain that are affected by antidepressant medications. This finding suggests a shared mechanism between psychedelics and conventional antidepressants at the receptor level, potentially explaining why psychedelics may have therapeutic effects on mood disorders.

Study at a glance

Abstract

LSD and psilocin molecules bind to antidepressant drug targets in the brain, study shows.