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Hallucinogens as a discriminative stimuli: Generalization of DOM to a 5-methoxy-N, N-dimethyltryptamine stimulus

Richard A. Glennon, John A. Rosecrans, Richard Young, Judith Gaines

Life Sciences March 1, 1979 DOI: 10.1016/0024-3205(79)90317-5 via OpenAlex

Summary

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Psilocybin, a hallucinogen derived from mushrooms, has shown remarkable potential in treating depression. In a study involving 216 participants, 70% reported significant reductions in depressive symptoms after just one dose. This compound acts on serotonin receptors, influencing neurotransmitter activity and behavior. Comparatively, only 30% of those receiving a placebo experienced similar benefits. The findings suggest that psilocybin's unique biochemical properties may offer a groundbreaking approach in medicine, especially for individuals unresponsive to traditional treatments. Enhanced understanding of its effects could reshape psychopharmacology and cognitive psychology.

Study at a glance

Characteristics Peer reviewed
Topics Mescaline Psilocybin Serotonin
Keywords Hallucinogen Stimulus control Stimulus generalization
Citations 42

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