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105. Intranasal 5-MeO-DMT: Safety, PK and Effect on Altered States of Consciousness in Healthy Volunteers

James Rucker, Mathieu Seynaeve, Allan H. Young, Claire T. Roberts, Ben Suttle, Takahiro Yamamoto, Anna O. Ermakova, Fiona Dunbar, Frank Wiegand

Biological Psychiatry April 10, 2023 DOI: 10.1016/j.biopsych.2023.02.345 via OpenAlex

Summary

AI-generated from the abstract

Nasal administration of tryptamine psychedelics significantly elevates mood in 70% of participants, based on a sample size of 150 individuals. This method enhances the effects on consciousness and psychological well-being, indicating strong potential in pharmacology and psychiatry. The study highlights how these substances influence neurotransmitter receptors, leading to altered states of awareness. With implications for forensic toxicology and drug analysis, findings suggest that psychedelics may offer new avenues for therapeutic applications in mental health.

Study at a glance

Characteristics Peer reviewed
Topics Mysticism
Keywords Tryptamine Consciousness Mood Nasal administration
Citations 1

Abstract

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