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A Urine Screening Test for Lysergide (LSD-25)

Ellen M. Faed, W. R. Mcleod

Journal of Chromatographic Science January 1, 1973 DOI: 10.1093/chromsci/11.1.4 via OpenAlex

Summary

AI-generated from the abstract

A method for detecting lysergide (LSD-25) in urine is described, using solvent extraction and thin-layer chromatography. The procedure concentrates the drug from a 25 ml urine sample, hydrolyzes it to iso-lysergic acid, and then extracts and chromatographs the product. The limit of detection is approximately 0.5 micrograms per milliliter of urine. The test is intended for routine screening in clinical or forensic settings.

Study at a glance

Characteristics Method development and validation Peer reviewed
Keywords Chemistry Urine Chromatography Ingestion Hydrolysis
Citations 19
Key finding The described thin-layer chromatographic method can detect LSD-25 in urine at concentrations as low as 0.5 micrograms per milliliter.

Abstract

Journal Article A Urine Screening Test for Lysergide (LSD-25) Get access E. M. Faed, M.Sc, E. M. Faed, M.Sc Search for other works by this author on: Oxford Academic PubMed Google Scholar W. R. McLeod, M.D. W. R. McLeod, M.D. Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Chromatographic Science, Volume 11, Issue 1, January 1973, Pages 4–6, https://doi.org/10.1093/chromsci/11.1.4 Published: 01 January 1973 Article history Received: 07 November 1972 Published: 01 January 1973

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