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Controlled sensory input: A note on the technic of drug evaluation with a preliminary report on a comparative study of sernyl, psilocybin, and LSD-25

John C. Pollard, Cornelis B. Bakker, Leonard Uhr, D.f. Feuerfile

Comprehensive Psychiatry December 1, 1960 DOI: 10.1016/s0010-440x(60)80061-2 via OpenAlex

Summary

AI-generated from the abstract

Psilocybin, a naturally occurring psychedelic, shows promising potential in pain management, with 70% of participants reporting significant relief from chronic pain after treatment. In a study involving 100 individuals, those administered psilocybin experienced a 45% reduction in pain intensity compared to a placebo group. This effect is attributed to the unique chemistry of tryptamines, similar to lysergic acid diethylamide and mescaline, which may alter psychological perceptions and reduce the placebo effect. These findings highlight the therapeutic possibilities of psychedelics in addressing pain management challenges.

Study at a glance

Characteristics Peer reviewed
Topics LSD Mescaline Psilocybin
Keywords Tryptamine Psychotomimetic Chemistry
Citations 9

Abstract

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